Abstract
A silicon nanowire (SiNW) biosensor for label-free and real-time detection has been fabricated by complementary metal-oxide semiconductor (CMOS) technology. For the detection of prostate-specific antigen (PSA) used as a biomarker of prostate cancer the SiNW surface was modified to immobilise the antibody of PSA (anti-PSA). Real-time monitoring reveals the change in conductivity of the SiNW on specific binding of PSA to anti-PSA. For 355 nm SiNW, the response to 10 ng/ml of PSA was 7.3%.
Original language | English |
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Journal | Electronics Letters |
Volume | 44 |
Issue number | 16 |
DOIs | |
Publication status | Published - 2008 |
ASJC Scopus subject areas
- Electrical and Electronic Engineering