Fabrication and evaluation of polymeric microvalve using the pH-responsive hydrogel microsphere

Ji Young Park, D. J. Kim, S. R. Kim, J. Y. Baek, Kyung Sun, Sang Hoon Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this paper, we propose a new fabrication method of pH-responsive microfluidic valves and suggest the feasibility as a microminiature systems without peripheral devices. Conventionally, in-situ photopolymerization method has been employed to build the micro functional structure inside microfluidic channel. Here, we suggest a new method allowing the mass production of stimuli-responsive microsystem through the use of pre-made microstructure as actuating element like assembly of commercial products in the factory. We have massively fabricated pH-responsive microspheres that act as actuating component through the use of PDMSbased microfluidic apparatus and ‘on the fly’ photopolymerization method. By the incorporation of this microsphere into the microvalve during the fabrication process, we have produced the pH-responsive microfluidic valve in a simple way. The operation and the function of the fabricated microvalve were evaluated through the diverse experiments. The microvalve was successfully fabricated, and functioned well according to the pH change.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalUnknown Journal
Volume14
Issue number1
Publication statusPublished - 2007

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Hydrogel
Microspheres
Microfluidics
Hydrogels
Fabrication
Photopolymerization
Microsystems
Industrial plants
Microstructure
Experiments

Keywords

  • Drug delivery
  • Microfluidic
  • Microsphere
  • Microvalve
  • pH-responsive

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Fabrication and evaluation of polymeric microvalve using the pH-responsive hydrogel microsphere. / Park, Ji Young; Kim, D. J.; Kim, S. R.; Baek, J. Y.; Sun, Kyung; Lee, Sang Hoon.

In: Unknown Journal, Vol. 14, No. 1, 2007, p. 294-297.

Research output: Contribution to journalArticle

Park, Ji Young ; Kim, D. J. ; Kim, S. R. ; Baek, J. Y. ; Sun, Kyung ; Lee, Sang Hoon. / Fabrication and evaluation of polymeric microvalve using the pH-responsive hydrogel microsphere. In: Unknown Journal. 2007 ; Vol. 14, No. 1. pp. 294-297.
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