Abstract
In this paper, we report a novel method for the microfabrication of arrays of concave and convex chambers with different diameters and curvatures. We used these structures to study the behavior of cultured mouse fibroblasts and human mesenchymal stem cells, and revealed important cellular behaviors of them. Therefore, our physiological studies indicate that the cultured fibroblast cells and human mesenchymal stem cells can sense micro-scale curvatures and actively respond by "escaping" from concave microwells.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1153-1155 |
| Number of pages | 3 |
| ISBN (Print) | 9780979806421 |
| Publication status | Published - 2009 Jan 1 |
| Event | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of Duration: 2009 Nov 1 → 2009 Nov 5 |
Other
| Other | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 |
|---|---|
| Country | Korea, Republic of |
| City | Jeju |
| Period | 09/11/1 → 09/11/5 |
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ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
Cite this
Lee, D. H., Park, J. Y., Lee, E. J., Kim, C. B., & Lee, S. H. (2009). Fabrication of 3D curved microstructures using thin PDMS membranes and motion tendency of cells. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1153-1155). Chemical and Biological Microsystems Society.