Abstract
In this paper, we report a novel method for the microfabrication of arrays of concave and convex chambers with different diameters and curvatures. We used these structures to study the behavior of cultured mouse fibroblasts and human mesenchymal stem cells, and revealed important cellular behaviors of them. Therefore, our physiological studies indicate that the cultured fibroblast cells and human mesenchymal stem cells can sense micro-scale curvatures and actively respond by "escaping" from concave microwells.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1153-1155 |
| Number of pages | 3 |
| ISBN (Print) | 9780979806421 |
| Publication status | Published - 2009 Jan 1 |
| Event | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of Duration: 2009 Nov 1 → 2009 Nov 5 |
Other
| Other | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 |
|---|---|
| Country | Korea, Republic of |
| City | Jeju |
| Period | 09/11/1 → 09/11/5 |
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ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
Cite this
Fabrication of 3D curved microstructures using thin PDMS membranes and motion tendency of cells. / Lee, Dae Ho; Park, Joong Yull; Lee, Eun Joong; Kim, Chang Beom; Lee, Sang Hoon.
Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. p. 1153-1155.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Fabrication of 3D curved microstructures using thin PDMS membranes and motion tendency of cells
AU - Lee, Dae Ho
AU - Park, Joong Yull
AU - Lee, Eun Joong
AU - Kim, Chang Beom
AU - Lee, Sang Hoon
PY - 2009/1/1
Y1 - 2009/1/1
N2 - In this paper, we report a novel method for the microfabrication of arrays of concave and convex chambers with different diameters and curvatures. We used these structures to study the behavior of cultured mouse fibroblasts and human mesenchymal stem cells, and revealed important cellular behaviors of them. Therefore, our physiological studies indicate that the cultured fibroblast cells and human mesenchymal stem cells can sense micro-scale curvatures and actively respond by "escaping" from concave microwells.
AB - In this paper, we report a novel method for the microfabrication of arrays of concave and convex chambers with different diameters and curvatures. We used these structures to study the behavior of cultured mouse fibroblasts and human mesenchymal stem cells, and revealed important cellular behaviors of them. Therefore, our physiological studies indicate that the cultured fibroblast cells and human mesenchymal stem cells can sense micro-scale curvatures and actively respond by "escaping" from concave microwells.
KW - 3D microstructure
KW - Cellular behavior
KW - Concave
KW - Convex
UR - http://www.scopus.com/inward/record.url?scp=84901809595&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901809595&partnerID=8YFLogxK
M3 - Conference contribution
SN - 9780979806421
SP - 1153
EP - 1155
BT - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
ER -