Fabrication of a piezoelectric ceramic using a spark plasma sintering technique and its application for a focused ultrasound-assisted lipolysis system

Kyung-Hwan Cho, Bong Geun Choi, Byoung Gook Loh, Zhong Soo Lim, Do-Hoon Kim, Byung Joon Ko, Yang-Hyun Kim, Seon Mee Kim, Kwang Bo Shim

Research output: Contribution to journalArticle

Abstract

Pb(Zr0.5Ti0.5)O3 piezoelectric ceramics have been prepared using a spark plasma sintering technique and adapted for the design of a noninvasive lipolysis system, as the traditional ultrasound-assisted lipolysis system (UALS) is extremely invasive, significantly increasing the risk of morbidity and mortality. In order to transfer high sonic energy into a certain depth of skin (subcutaneous area) with minimal damage to superficial skin, a focusing acoustic wave design was developed. The selfdesigned UALS device was found to be very effective in destructing the adipocytes around the focused area in animal experiments. The focusing probe with bio-applicable piezoelectric materials shows great promise for future clinical applications.

Original languageEnglish
Pages (from-to)610-614
Number of pages5
JournalJournal of Ceramic Processing Research
Volume12
Issue number5
Publication statusPublished - 2011 Dec 19

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Keywords

  • Adipocyte
  • Focused ultrasound
  • Piezoelectric ceramic
  • Ultrasound-assisted lipolysis

ASJC Scopus subject areas

  • Ceramics and Composites

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