Fabrication of Hollow-type Silicon Microneedle Array Using Microfabrication Technology

Seung Kook Kim, Jong Hyeon Chang, Byoungmin Kim, Sang Sik Yang, In Sik Hwang, James Jungho Pak

Research output: Contribution to journalArticle

Abstract

Hollow-type microneedle array can be used for painless, continuous and stable drug delivery through a human skin. The needles must be sharp and have sufficient length in order to penetrate the epidermis. An array of hollow-type silicon microneedles was fabricated by using deep reactive ion etching and HNA wet etching with two oxide masks. Isotropic etching was used to create tapered tips of the needles, and anisotropic etching of Bosch process was used to make the extended length and holes of microneedles. The microneedles were formed by three steps of isotropic, anisotropic, and isotropic etching in order. The holes were made by one anisotropic etching step. The fabricated microneedles have 170 μm width, 40 μm hole diameter and 230 μm length.

Original languageEnglish
Pages (from-to)2221-2224
Number of pages4
JournalTransactions of the Korean Institute of Electrical Engineers
Volume56
Issue number12
Publication statusPublished - 2007 Dec 1

Fingerprint

Anisotropic etching
Microfabrication
Needles
Etching
Fabrication
Silicon
Wet etching
Reactive ion etching
Drug delivery
Masks
Skin
Oxides

Keywords

  • Anisotropic etching
  • Deep reactive ion etching
  • HNA wet etching
  • Hollow-type silicon micronedle array
  • Isotropic etching

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Fabrication of Hollow-type Silicon Microneedle Array Using Microfabrication Technology. / Kim, Seung Kook; Chang, Jong Hyeon; Kim, Byoungmin; Yang, Sang Sik; Hwang, In Sik; Pak, James Jungho.

In: Transactions of the Korean Institute of Electrical Engineers, Vol. 56, No. 12, 01.12.2007, p. 2221-2224.

Research output: Contribution to journalArticle

Kim, Seung Kook ; Chang, Jong Hyeon ; Kim, Byoungmin ; Yang, Sang Sik ; Hwang, In Sik ; Pak, James Jungho. / Fabrication of Hollow-type Silicon Microneedle Array Using Microfabrication Technology. In: Transactions of the Korean Institute of Electrical Engineers. 2007 ; Vol. 56, No. 12. pp. 2221-2224.
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