Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions

Taegon Kang, Roey J. Amir, Anzar Khan, Kaoru Ohshimizu, Jasmine N. Hunt, Kulandaivelu Sivanandan, Maria I. Montañez, Michael Malkoch, Mitsuru Ueda, Craig J. Hawker

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

A simple synthetic strategy has been developed for accessing internally functionalized dendrimers. The key feature of this approach is the use of two orthogonal and efficient reactions - 'epoxy-amine' and 'thiol-ene' coupling - for rapid growth of the dendritic scaffold. This sequence of reactions allows for the introduction of reactive hydroxyl groups at each dendritic layer.

Original languageEnglish
Pages (from-to)1556-1558
Number of pages3
JournalChemical Communications
Volume46
Issue number9
DOIs
Publication statusPublished - 2010 Feb 24
Externally publishedYes

Fingerprint

Dendrimers
Sulfhydryl Compounds
Scaffolds
Hydroxyl Radical
Amines
Growth

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Kang, T., Amir, R. J., Khan, A., Ohshimizu, K., Hunt, J. N., Sivanandan, K., ... Hawker, C. J. (2010). Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions. Chemical Communications, 46(9), 1556-1558. https://doi.org/10.1039/b921598k

Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions. / Kang, Taegon; Amir, Roey J.; Khan, Anzar; Ohshimizu, Kaoru; Hunt, Jasmine N.; Sivanandan, Kulandaivelu; Montañez, Maria I.; Malkoch, Michael; Ueda, Mitsuru; Hawker, Craig J.

In: Chemical Communications, Vol. 46, No. 9, 24.02.2010, p. 1556-1558.

Research output: Contribution to journalArticle

Kang, T, Amir, RJ, Khan, A, Ohshimizu, K, Hunt, JN, Sivanandan, K, Montañez, MI, Malkoch, M, Ueda, M & Hawker, CJ 2010, 'Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions', Chemical Communications, vol. 46, no. 9, pp. 1556-1558. https://doi.org/10.1039/b921598k
Kang, Taegon ; Amir, Roey J. ; Khan, Anzar ; Ohshimizu, Kaoru ; Hunt, Jasmine N. ; Sivanandan, Kulandaivelu ; Montañez, Maria I. ; Malkoch, Michael ; Ueda, Mitsuru ; Hawker, Craig J. / Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions. In: Chemical Communications. 2010 ; Vol. 46, No. 9. pp. 1556-1558.
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