Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Woo Sub Yoon, Su Jung Lee, Seung Kyu Kang, Deok-Chan Ha, Jae Du Ha

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

Original languageEnglish
Pages (from-to)4492-4494
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number31
DOIs
Publication statusPublished - 2009 Aug 5

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Pyridines
Palladium
Heating
Ligands
2-bromophenol
palladium(II) acetate

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction. / Yoon, Woo Sub; Lee, Su Jung; Kang, Seung Kyu; Ha, Deok-Chan; Ha, Jae Du.

In: Tetrahedron Letters, Vol. 50, No. 31, 05.08.2009, p. 4492-4494.

Research output: Contribution to journalArticle

Yoon, Woo Sub ; Lee, Su Jung ; Kang, Seung Kyu ; Ha, Deok-Chan ; Ha, Jae Du. / Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction. In: Tetrahedron Letters. 2009 ; Vol. 50, No. 31. pp. 4492-4494.
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