Factors affecting the clearance of high-risk human papillomavirus infection and the progression of cervical intraepithelial neoplasia

J. W. Kim, S. H. Song, C. H. Jin, J. K. Lee, N. W. Lee, K. W. Lee

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

OBJECTIVE: This study aimed to identify from HPV infection and 66/817 patients factors that predict clearance of high-risk (8.1%) progressed to CIN 2 or higher. Age, human papillomavirus (HPV) infection parity, cytology and viral load at and progression to cervical intraepithelial diagnosis were significantly and inversely neoplasia (CIN) 2 or higher, in women associated with HPV clearance. Cytology, with normal cervical histology or CIN 1. viral load and presence of CIN 1 lesions METHODS: A retrospective analysis was were significantly associated with lesion performed on 817 high-risk HPV-infected progression. CONCLUSIONS: Cytology and women with histologically verified CIN 1 high-risk HPV viral load may be useful or normal cervical histology. Patients were markers for the likelihood of high-risk followed-up for a maximum of 24 months. HPV clearance and lesion progression. Cervical HPV DNA tests were performed at Histological status, parity and marital every visit. RESULTS: At the end of follow- status may also be useful factors to up, 648/817 (79.3%) patients were free consider when predicting progression.

Original languageEnglish
Pages (from-to)486-496
Number of pages11
JournalJournal of International Medical Research
Volume40
Issue number2
DOIs
Publication statusPublished - 2012

Keywords

  • Cervical intraepithelial neoplasia
  • Human papillomavirus
  • Progression
  • Viral clearance
  • Viral load

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

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