Fatty acids and insulin resistance: A perfect storm

Seung-Hoi Koo, Marc Montminy

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.

Original languageEnglish
Pages (from-to)449-450
Number of pages2
JournalMolecular Cell
Volume21
Issue number4
DOIs
Publication statusPublished - 2006 Feb 17
Externally publishedYes

Fingerprint

Forkhead Transcription Factors
Type 2 Diabetes Mellitus
Coronary Disease
Insulin Resistance
Fatty Acids
Insulin
Liver

ASJC Scopus subject areas

  • Molecular Biology

Cite this

Fatty acids and insulin resistance : A perfect storm. / Koo, Seung-Hoi; Montminy, Marc.

In: Molecular Cell, Vol. 21, No. 4, 17.02.2006, p. 449-450.

Research output: Contribution to journalArticle

Koo, Seung-Hoi ; Montminy, Marc. / Fatty acids and insulin resistance : A perfect storm. In: Molecular Cell. 2006 ; Vol. 21, No. 4. pp. 449-450.
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