Fine-needle aspiration cytology of pleuropulmonary blastoma: A case report with unusual features

Bong Kyung Shin, Min Kyung Kim, Seong Hwan Park, Chung Yeul Kim, Seong Jin Cho, Kwang Chul Lee, Kwang Taik Kim, Yu Hwan Oh, Insun Kim, Han Kyeom Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Pleuropulmonary blastoma (PPB) is a rare and aggressive intrathoracic neoplasm of childhood, typically presenting as a pulmonary and/or pleural-based mass with cystic, solid, or combined features. Histologically, the tumor is well characterized with a mixture of primitive mesenchymal and variably differentiated sarcomatous components, and the cytologic features described in the three previous reports are also compatible to the histologic ones. Now, we present another case of PPB showing unusual features. A 3-yr-old boy presented with a pleural- or chest wall-based tumor. The fine-needle aspiration cytologic smears were highly cellular with poorly differentiated cells showing variable size and shape rather than those of typical blastemal cells. The histologic findings were also distinctive, exhibiting diffuse sheets of poorly differentiated cells without typical blastemal cell component. Diagnosis was confirmed by the support of immunohistochemical and ultrastructural features. The patient underwent a typical aggressive clinical course to death within 8 mo after diagnosis.

Original languageEnglish
Pages (from-to)397-402
Number of pages6
JournalDiagnostic Cytopathology
Volume25
Issue number6
DOIs
Publication statusPublished - 2001 Dec 13

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Fine Needle Biopsy
Cell Biology
Neoplasms
Thoracic Wall
Cellular Structures
Lung
Pleuropulmonary blastoma

Keywords

  • Fine-needle aspiration cytology
  • Pleuropulmonary blastoma
  • Unusual features

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

Fine-needle aspiration cytology of pleuropulmonary blastoma : A case report with unusual features. / Shin, Bong Kyung; Kim, Min Kyung; Park, Seong Hwan; Kim, Chung Yeul; Cho, Seong Jin; Lee, Kwang Chul; Kim, Kwang Taik; Oh, Yu Hwan; Kim, Insun; Kim, Han Kyeom.

In: Diagnostic Cytopathology, Vol. 25, No. 6, 13.12.2001, p. 397-402.

Research output: Contribution to journalArticle

Shin, Bong Kyung ; Kim, Min Kyung ; Park, Seong Hwan ; Kim, Chung Yeul ; Cho, Seong Jin ; Lee, Kwang Chul ; Kim, Kwang Taik ; Oh, Yu Hwan ; Kim, Insun ; Kim, Han Kyeom. / Fine-needle aspiration cytology of pleuropulmonary blastoma : A case report with unusual features. In: Diagnostic Cytopathology. 2001 ; Vol. 25, No. 6. pp. 397-402.
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