@article{19ec441e19cc4ba9a704c85a557f1c10,
title = "Flow reaction system for the synthesis of benzoylacetonitrile via the reaction of amides and acetonitrile",
abstract = "Unactivated amides, such as N,N-dimethylbenzamide, react with acetonitrile in the presence of LiHMDS under flow reaction conditions to afford corresponding benzoylacetonitriles in good yields. The sequential flow reaction system is also applicable to the synthesis of benzoylacetonitrile from N-methylbenzamide.",
keywords = "Amide, Benzoylacetonitrile, C-N bond activation, Flow reaction, LiHMDS",
author = "Joonyoung Kim and Park, {Myeong Seong} and Sunwoo Lee and Song, {Kwang Ho}",
note = "Funding Information: This research was supported by the grant funded by the Korean government ( MSIT ) ( NRF-2021R1A2C1005169 ) and the Korea University . Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center. Funding Information: This research was supported by the grant funded by the Korean government (MSIT) (NRF-2021R1A2C1005169) and the Korea University. Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",
year = "2022",
month = nov,
day = "23",
doi = "10.1016/j.tetlet.2022.154201",
language = "English",
volume = "111",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
}