Fluorescent sensing of pyrophosphate and ATP in 100% aqueous solution using a fluorescein derivative and Mn2+

K. M K Swamy, Soo Kyung Kwon, Ha Na Lee, S. M. Shantha Kumar, Jong Seung Kim, Juyoung Yoon

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

A new fluorescein derivative has been synthesized for the detection of pyrophosphate (PPi) and ATP in 100% aqueous solution. Chemosensor 1 in the presence of Mn2+ (2.5 equiv) displayed selective fluorescent enhancements with PPi and ATP at pH 7.4. among the anions examined. The association constant of 1 in the presence of Mn2+ with PPi and ATP was calculated as 4.2 × 104 and 3.5 × 104 M-1.

Original languageEnglish
Pages (from-to)8683-8686
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number49
DOIs
Publication statusPublished - 2007 Dec 3

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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