Fractionation and angiotensin I-converting enzyme (ACE) inhibitory activity of gelatin hydrolysates from by-products of Alaska pollock surimi

Chan Ho Park, Hyung Jun Kim, Kyung Tae Kang, Jae W. Park, Jin Soo Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)


Gelatin hydrolysates with a high inhibitory activity against angiotensin I-converting enzyme (ACE) were fractionated from Alaska pollock surimi refiner discharge. The ACE-inhibitory activity, expressed as IC50 (mg/mL), was highest (0.49 mg/mL) in gelatin hydrolysates formed by sequential 2-hr treatments of Pronase and Flavourzyme. After fractionation through four different membrane filters with molecular weight cut-offs of 3, 5, 10, and 30 kDa, the highest ACE-inhibitory activity (0.21 mg/mL) was observed with the 3-kDa filtrate.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalFisheries and Aquatic Science
Issue number2
Publication statusPublished - 2009 Jun 1
Externally publishedYes


ASJC Scopus subject areas

  • Aquatic Science
  • Biochemistry
  • Molecular Biology
  • Oceanography

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