Frequency and severity of carpal tunnel syndrome according to level of cervical radiculopathy

Double crush syndrome?

Hee Kyu Kwon, Miriam Hwang, Dae Won Yoon

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Objective: The double crush hypothesis (DC) proposes that a proximal lesion along an axon predisposes it to injury at a more distal site along its course through impaired axoplasmic flow. The frequency and severity of carpal tunnel syndrome (CTS) according to the level of cervical radiculopathy were investigated to evaluate the hypothesis of DC. Methods: The frequency of CTS was investigated in 277 patients with C6, C7 or C8 radiculopathies and correlation between CTS and radiculopathy level was determined. We also investigated whether the degrees of abnormal sensory responses were more severe in C6, C7 radiculopathies and whether motor responses were more severe in C8 radiculopathy. Results: Thirty-nine patients were diagnosed with CTS and concomitant cervical radiculopathy at the C6, 7, or C8 root levels. The frequency of coexisting CTS was not statistically different according to the level of radiculopathy. The electrophysiologic results revealed no significant correlation between median sensory parameters and C6, C7 cases, and no relationship was observed between median motor responses and C8 radiculopathy. Conclusions: The frequency and electrophysiologic data of CTS analyzed according to cervical radiculopathy level do not support a neurophysiological explanation. Significance: Based on this study, the DC hypothesis could not be supported.

Original languageEnglish
Pages (from-to)1256-1259
Number of pages4
JournalClinical Neurophysiology
Volume117
Issue number6
DOIs
Publication statusPublished - 2006 Jun 1

Fingerprint

Crush Syndrome
Radiculopathy
Carpal Tunnel Syndrome
Axonal Transport
Axons

Keywords

  • Carpal tunnel syndrome
  • Cervical radiculopathy
  • Double crush syndrome

ASJC Scopus subject areas

  • Sensory Systems
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Frequency and severity of carpal tunnel syndrome according to level of cervical radiculopathy : Double crush syndrome? / Kwon, Hee Kyu; Hwang, Miriam; Yoon, Dae Won.

In: Clinical Neurophysiology, Vol. 117, No. 6, 01.06.2006, p. 1256-1259.

Research output: Contribution to journalArticle

@article{2c5564bf4b894d3c88a0d363d424147f,
title = "Frequency and severity of carpal tunnel syndrome according to level of cervical radiculopathy: Double crush syndrome?",
abstract = "Objective: The double crush hypothesis (DC) proposes that a proximal lesion along an axon predisposes it to injury at a more distal site along its course through impaired axoplasmic flow. The frequency and severity of carpal tunnel syndrome (CTS) according to the level of cervical radiculopathy were investigated to evaluate the hypothesis of DC. Methods: The frequency of CTS was investigated in 277 patients with C6, C7 or C8 radiculopathies and correlation between CTS and radiculopathy level was determined. We also investigated whether the degrees of abnormal sensory responses were more severe in C6, C7 radiculopathies and whether motor responses were more severe in C8 radiculopathy. Results: Thirty-nine patients were diagnosed with CTS and concomitant cervical radiculopathy at the C6, 7, or C8 root levels. The frequency of coexisting CTS was not statistically different according to the level of radiculopathy. The electrophysiologic results revealed no significant correlation between median sensory parameters and C6, C7 cases, and no relationship was observed between median motor responses and C8 radiculopathy. Conclusions: The frequency and electrophysiologic data of CTS analyzed according to cervical radiculopathy level do not support a neurophysiological explanation. Significance: Based on this study, the DC hypothesis could not be supported.",
keywords = "Carpal tunnel syndrome, Cervical radiculopathy, Double crush syndrome",
author = "Kwon, {Hee Kyu} and Miriam Hwang and Yoon, {Dae Won}",
year = "2006",
month = "6",
day = "1",
doi = "10.1016/j.clinph.2006.02.013",
language = "English",
volume = "117",
pages = "1256--1259",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd",
number = "6",

}

TY - JOUR

T1 - Frequency and severity of carpal tunnel syndrome according to level of cervical radiculopathy

T2 - Double crush syndrome?

AU - Kwon, Hee Kyu

AU - Hwang, Miriam

AU - Yoon, Dae Won

PY - 2006/6/1

Y1 - 2006/6/1

N2 - Objective: The double crush hypothesis (DC) proposes that a proximal lesion along an axon predisposes it to injury at a more distal site along its course through impaired axoplasmic flow. The frequency and severity of carpal tunnel syndrome (CTS) according to the level of cervical radiculopathy were investigated to evaluate the hypothesis of DC. Methods: The frequency of CTS was investigated in 277 patients with C6, C7 or C8 radiculopathies and correlation between CTS and radiculopathy level was determined. We also investigated whether the degrees of abnormal sensory responses were more severe in C6, C7 radiculopathies and whether motor responses were more severe in C8 radiculopathy. Results: Thirty-nine patients were diagnosed with CTS and concomitant cervical radiculopathy at the C6, 7, or C8 root levels. The frequency of coexisting CTS was not statistically different according to the level of radiculopathy. The electrophysiologic results revealed no significant correlation between median sensory parameters and C6, C7 cases, and no relationship was observed between median motor responses and C8 radiculopathy. Conclusions: The frequency and electrophysiologic data of CTS analyzed according to cervical radiculopathy level do not support a neurophysiological explanation. Significance: Based on this study, the DC hypothesis could not be supported.

AB - Objective: The double crush hypothesis (DC) proposes that a proximal lesion along an axon predisposes it to injury at a more distal site along its course through impaired axoplasmic flow. The frequency and severity of carpal tunnel syndrome (CTS) according to the level of cervical radiculopathy were investigated to evaluate the hypothesis of DC. Methods: The frequency of CTS was investigated in 277 patients with C6, C7 or C8 radiculopathies and correlation between CTS and radiculopathy level was determined. We also investigated whether the degrees of abnormal sensory responses were more severe in C6, C7 radiculopathies and whether motor responses were more severe in C8 radiculopathy. Results: Thirty-nine patients were diagnosed with CTS and concomitant cervical radiculopathy at the C6, 7, or C8 root levels. The frequency of coexisting CTS was not statistically different according to the level of radiculopathy. The electrophysiologic results revealed no significant correlation between median sensory parameters and C6, C7 cases, and no relationship was observed between median motor responses and C8 radiculopathy. Conclusions: The frequency and electrophysiologic data of CTS analyzed according to cervical radiculopathy level do not support a neurophysiological explanation. Significance: Based on this study, the DC hypothesis could not be supported.

KW - Carpal tunnel syndrome

KW - Cervical radiculopathy

KW - Double crush syndrome

UR - http://www.scopus.com/inward/record.url?scp=33744788905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33744788905&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2006.02.013

DO - 10.1016/j.clinph.2006.02.013

M3 - Article

VL - 117

SP - 1256

EP - 1259

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 6

ER -