Fullerene attachment enhances performance of a DNA nanomachine

Su Ryon Shin, Kyeong Sik Jin, Chang Kee Lee, Sun I. Kim, Geoffrey M. Spinks, Insuk So, Ju Hong Jeon, Tong Mook Kang, Ji Young Mun, Sung Sik Han, Moonhor Ree, Seon Jeong Kim

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The attachment of fullerenes to a DNA motif significantly improves the molecular switching and stability of pH driven enthalpic molecular machine has been reported. DNA is considered as a versatile building block for molecular machines because of its well defined structure and controllable intermolecular interactions. The pH-induced transformation of the DNA was confirmed by Circular Dichroism (CD) spectroscopy and changes occurring in DNA motif were analyzed using three-dimensional molecular analysis by Small Angle X-ray Scattering (SAXS). Hydrophobic interactions between the terminal fullerenes in the folded i-motif conformation increased the machines power stroke and force generated. No reduction in cycling speed or cycling stability with changing pH was observed as a result of attachment of the fullerene.

Original languageEnglish
Pages (from-to)1907-1910
Number of pages4
JournalAdvanced Materials
Volume21
Issue number19
DOIs
Publication statusPublished - 2009 May 18

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Fullerenes
DNA
Circular dichroism spectroscopy
X ray scattering
Conformations

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Shin, S. R., Jin, K. S., Lee, C. K., Kim, S. I., Spinks, G. M., So, I., ... Kim, S. J. (2009). Fullerene attachment enhances performance of a DNA nanomachine. Advanced Materials, 21(19), 1907-1910. https://doi.org/10.1002/adma.200803429

Fullerene attachment enhances performance of a DNA nanomachine. / Shin, Su Ryon; Jin, Kyeong Sik; Lee, Chang Kee; Kim, Sun I.; Spinks, Geoffrey M.; So, Insuk; Jeon, Ju Hong; Kang, Tong Mook; Mun, Ji Young; Han, Sung Sik; Ree, Moonhor; Kim, Seon Jeong.

In: Advanced Materials, Vol. 21, No. 19, 18.05.2009, p. 1907-1910.

Research output: Contribution to journalArticle

Shin, SR, Jin, KS, Lee, CK, Kim, SI, Spinks, GM, So, I, Jeon, JH, Kang, TM, Mun, JY, Han, SS, Ree, M & Kim, SJ 2009, 'Fullerene attachment enhances performance of a DNA nanomachine', Advanced Materials, vol. 21, no. 19, pp. 1907-1910. https://doi.org/10.1002/adma.200803429
Shin SR, Jin KS, Lee CK, Kim SI, Spinks GM, So I et al. Fullerene attachment enhances performance of a DNA nanomachine. Advanced Materials. 2009 May 18;21(19):1907-1910. https://doi.org/10.1002/adma.200803429
Shin, Su Ryon ; Jin, Kyeong Sik ; Lee, Chang Kee ; Kim, Sun I. ; Spinks, Geoffrey M. ; So, Insuk ; Jeon, Ju Hong ; Kang, Tong Mook ; Mun, Ji Young ; Han, Sung Sik ; Ree, Moonhor ; Kim, Seon Jeong. / Fullerene attachment enhances performance of a DNA nanomachine. In: Advanced Materials. 2009 ; Vol. 21, No. 19. pp. 1907-1910.
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