Functional nanomaterial-based amplified bio-detection strategies

Jongho Jeon, Dong Kwon Lim, Jwa Min Nam

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

In the development of bio-detection assays that could be useful in a variety of applications such as medical diagnostic and biowarfare agent detection, improving assay sensitivity might be the foremost important task. To address this assay sensitivity issue, researchers have synthesized highly functional nanomaterials and used their structures and functions to amplify detection signals often without using enzymatic amplification that is essential in the polymerase chain reaction (PCR). Here, we review various amplification methods that facilitate ultrahigh assay sensitivity using functional nanomaterials. We describe the basic principles, advantages, limitations and perspectives of amplified bio-detection strategies based on optical, electrical, magnetic or mechanical properties of nanomaterials.

Original languageEnglish
Pages (from-to)2107-2117
Number of pages11
JournalJournal of Materials Chemistry
Volume19
Issue number15
DOIs
Publication statusPublished - 2009
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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