Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury

Woon Ryoung Kim, Minjin Kang, Heejoo Park, Hyun Joo Ham, Hyunji Lee, Dongho Geum

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Recently, spinal cord researchers have focused on multifaceted approaches for the treatment of spinal cord injury (SCI). However, as there is no cure for the deficits produced by SCI, various therapeutic strategies have been examined using animal models. Due to the lack of standardized functional assessment tools for use in such models, it is important to choose a suitable animal model and precise behavioral test when evaluating the efficacy of potential SCI treatments. In the present review, we discuss recent evidence regarding functional recovery in various animal models of SCI, summarize the representative models currently used, evaluate recent cell-based therapeutic approaches, and aim to identify the most precise and appropriate scales for functional assessment in such research.

Original languageEnglish
Article number5160261
JournalStem Cells International
Volume2017
DOIs
Publication statusPublished - 2017

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Cell- and Tissue-Based Therapy
Spinal Cord Injuries
Animal Models
Therapeutics
Spinal Cord
Research Personnel
Research

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury. / Kim, Woon Ryoung; Kang, Minjin; Park, Heejoo; Ham, Hyun Joo; Lee, Hyunji; Geum, Dongho.

In: Stem Cells International, Vol. 2017, 5160261, 2017.

Research output: Contribution to journalReview article

Kim, Woon Ryoung ; Kang, Minjin ; Park, Heejoo ; Ham, Hyun Joo ; Lee, Hyunji ; Geum, Dongho. / Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury. In: Stem Cells International. 2017 ; Vol. 2017.
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