Abstract
A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
| Original language | English |
|---|---|
| Pages (from-to) | 483-489 |
| Number of pages | 7 |
| Journal | Korean Journal of Internal Medicine |
| Volume | 33 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2018 May 1 |
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Keywords
- Antigen-presenting cells
- Dendritic cells
- Th2 responses
ASJC Scopus subject areas
- Internal Medicine
Cite this
Fundamental role of dendritic cells in inducing Th2 responses. / Kim, Byoungjae; Kim, Tae-Hoon.
In: Korean Journal of Internal Medicine, Vol. 33, No. 3, 01.05.2018, p. 483-489.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Fundamental role of dendritic cells in inducing Th2 responses
AU - Kim, Byoungjae
AU - Kim, Tae-Hoon
PY - 2018/5/1
Y1 - 2018/5/1
N2 - A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
AB - A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
KW - Antigen-presenting cells
KW - Dendritic cells
KW - Th2 responses
UR - http://www.scopus.com/inward/record.url?scp=85047127517&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047127517&partnerID=8YFLogxK
U2 - 10.3904/kjim.2016.227
DO - 10.3904/kjim.2016.227
M3 - Review article
C2 - 29502361
AN - SCOPUS:85047127517
VL - 33
SP - 483
EP - 489
JO - Korean Journal of Internal Medicine
JF - Korean Journal of Internal Medicine
SN - 0494-4712
IS - 3
ER -