Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

Ron Mittler, YongSig Kim, Luhua Song, Jesse Coutu, Alicia Coutu, Sultan Ciftci-Yilmaz, Hojoung Lee, Becky Stevenson, Jian Kang Zhu

Research output: Contribution to journalArticle

224 Citations (Scopus)

Abstract

C2H2-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic stress. Constitutive expression of the C2H2-EAR zinc finger protein Zat10 in Arabidopsis was found to elevate the expression of reactive oxygen-defense transcripts and to enhance the tolerance of plants to salinity, heat and osmotic stress. Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses.

Original languageEnglish
Pages (from-to)6537-6542
Number of pages6
JournalFEBS Letters
Volume580
Issue number28-29
DOIs
Publication statusPublished - 2006 Dec 11
Externally publishedYes

Fingerprint

Zinc
Osmotic Pressure
Salinity
Mutation
Proteins
Oxygen
RNA Interference
Hot Temperature
CYS2-HIS2 Zinc Fingers
Arabidopsis Zat10 protein

Keywords

  • Abiotic stress
  • Arabidopsis thaliana
  • CH-zinc finger
  • EAR motif
  • Stress tolerance
  • Zat10

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Mittler, R., Kim, Y., Song, L., Coutu, J., Coutu, A., Ciftci-Yilmaz, S., ... Zhu, J. K. (2006). Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. FEBS Letters, 580(28-29), 6537-6542. https://doi.org/10.1016/j.febslet.2006.11.002

Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. / Mittler, Ron; Kim, YongSig; Song, Luhua; Coutu, Jesse; Coutu, Alicia; Ciftci-Yilmaz, Sultan; Lee, Hojoung; Stevenson, Becky; Zhu, Jian Kang.

In: FEBS Letters, Vol. 580, No. 28-29, 11.12.2006, p. 6537-6542.

Research output: Contribution to journalArticle

Mittler, R, Kim, Y, Song, L, Coutu, J, Coutu, A, Ciftci-Yilmaz, S, Lee, H, Stevenson, B & Zhu, JK 2006, 'Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress', FEBS Letters, vol. 580, no. 28-29, pp. 6537-6542. https://doi.org/10.1016/j.febslet.2006.11.002
Mittler R, Kim Y, Song L, Coutu J, Coutu A, Ciftci-Yilmaz S et al. Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. FEBS Letters. 2006 Dec 11;580(28-29):6537-6542. https://doi.org/10.1016/j.febslet.2006.11.002
Mittler, Ron ; Kim, YongSig ; Song, Luhua ; Coutu, Jesse ; Coutu, Alicia ; Ciftci-Yilmaz, Sultan ; Lee, Hojoung ; Stevenson, Becky ; Zhu, Jian Kang. / Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. In: FEBS Letters. 2006 ; Vol. 580, No. 28-29. pp. 6537-6542.
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