Gait freezing and speech disturbance in Parkinson's disease

Hee Kyung Park, Jong Yoon Yoo, Miseon Kwon, Jae Hong Lee, Sook Joung Lee, Sung Reul Kim, Mi Jung Kim, Myoung C. Lee, Sang Min Lee, Sun Ju Chung

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Gait freezing and speech disturbance are disabling axial features of Parkinson's disease (PD). However, the pathogenesis of these features remains unclear. We investigated the relation between changes in gait freezing and speech disturbance using visual and auditory cues in PD. 18 PD patients, comprising of 9 patients with freezing (PDGF) and 9 without gait freezing were studied. Patients performed a 7-m back-and-forth walk in a baseline state and with visual and auditory cues. Gait velocity, stride length and cadence were evaluated using a three-dimensional gait analysis system. For speech evaluation, patients read ten sentences in a baseline state and with visual and auditory cues. The time delay of speech initiation, speech rate and the number of repetitions per sentence were quantified. In PDGF patients, the increase in gait velocity positively correlated with the decrease in the time delay of the speech initiation. Also, the increase in the gait velocity and cadence positively correlated with the decrease in the number of repetitions per sentence. The increase in the stride length positively correlated with the increase in speech rate. Lastly, the increase in stride length positively correlated with the decrease in the number of repetitions per sentence. These findings suggest that there is a common pathomechanism of gait freezing and speech disturbance in PD.

Original languageEnglish
Pages (from-to)357-363
Number of pages7
JournalNeurological Sciences
Volume35
Issue number3
DOIs
Publication statusPublished - 2014 Mar 1
Externally publishedYes

Fingerprint

Gait
Freezing
Parkinson Disease
Language Development Disorders
Cues

Keywords

  • Auditory cue
  • Freezing of gait
  • Parkinson's disease
  • Speech
  • Visual cue

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Park, H. K., Yoo, J. Y., Kwon, M., Lee, J. H., Lee, S. J., Kim, S. R., ... Chung, S. J. (2014). Gait freezing and speech disturbance in Parkinson's disease. Neurological Sciences, 35(3), 357-363. https://doi.org/10.1007/s10072-013-1519-1

Gait freezing and speech disturbance in Parkinson's disease. / Park, Hee Kyung; Yoo, Jong Yoon; Kwon, Miseon; Lee, Jae Hong; Lee, Sook Joung; Kim, Sung Reul; Kim, Mi Jung; Lee, Myoung C.; Lee, Sang Min; Chung, Sun Ju.

In: Neurological Sciences, Vol. 35, No. 3, 01.03.2014, p. 357-363.

Research output: Contribution to journalArticle

Park, HK, Yoo, JY, Kwon, M, Lee, JH, Lee, SJ, Kim, SR, Kim, MJ, Lee, MC, Lee, SM & Chung, SJ 2014, 'Gait freezing and speech disturbance in Parkinson's disease', Neurological Sciences, vol. 35, no. 3, pp. 357-363. https://doi.org/10.1007/s10072-013-1519-1
Park, Hee Kyung ; Yoo, Jong Yoon ; Kwon, Miseon ; Lee, Jae Hong ; Lee, Sook Joung ; Kim, Sung Reul ; Kim, Mi Jung ; Lee, Myoung C. ; Lee, Sang Min ; Chung, Sun Ju. / Gait freezing and speech disturbance in Parkinson's disease. In: Neurological Sciences. 2014 ; Vol. 35, No. 3. pp. 357-363.
@article{a2d0fdf724944887819691c6d2048e2e,
title = "Gait freezing and speech disturbance in Parkinson's disease",
abstract = "Gait freezing and speech disturbance are disabling axial features of Parkinson's disease (PD). However, the pathogenesis of these features remains unclear. We investigated the relation between changes in gait freezing and speech disturbance using visual and auditory cues in PD. 18 PD patients, comprising of 9 patients with freezing (PDGF) and 9 without gait freezing were studied. Patients performed a 7-m back-and-forth walk in a baseline state and with visual and auditory cues. Gait velocity, stride length and cadence were evaluated using a three-dimensional gait analysis system. For speech evaluation, patients read ten sentences in a baseline state and with visual and auditory cues. The time delay of speech initiation, speech rate and the number of repetitions per sentence were quantified. In PDGF patients, the increase in gait velocity positively correlated with the decrease in the time delay of the speech initiation. Also, the increase in the gait velocity and cadence positively correlated with the decrease in the number of repetitions per sentence. The increase in the stride length positively correlated with the increase in speech rate. Lastly, the increase in stride length positively correlated with the decrease in the number of repetitions per sentence. These findings suggest that there is a common pathomechanism of gait freezing and speech disturbance in PD.",
keywords = "Auditory cue, Freezing of gait, Parkinson's disease, Speech, Visual cue",
author = "Park, {Hee Kyung} and Yoo, {Jong Yoon} and Miseon Kwon and Lee, {Jae Hong} and Lee, {Sook Joung} and Kim, {Sung Reul} and Kim, {Mi Jung} and Lee, {Myoung C.} and Lee, {Sang Min} and Chung, {Sun Ju}",
year = "2014",
month = "3",
day = "1",
doi = "10.1007/s10072-013-1519-1",
language = "English",
volume = "35",
pages = "357--363",
journal = "Neurological Sciences",
issn = "1590-1874",
publisher = "Springer-Verlag Italia",
number = "3",

}

TY - JOUR

T1 - Gait freezing and speech disturbance in Parkinson's disease

AU - Park, Hee Kyung

AU - Yoo, Jong Yoon

AU - Kwon, Miseon

AU - Lee, Jae Hong

AU - Lee, Sook Joung

AU - Kim, Sung Reul

AU - Kim, Mi Jung

AU - Lee, Myoung C.

AU - Lee, Sang Min

AU - Chung, Sun Ju

PY - 2014/3/1

Y1 - 2014/3/1

N2 - Gait freezing and speech disturbance are disabling axial features of Parkinson's disease (PD). However, the pathogenesis of these features remains unclear. We investigated the relation between changes in gait freezing and speech disturbance using visual and auditory cues in PD. 18 PD patients, comprising of 9 patients with freezing (PDGF) and 9 without gait freezing were studied. Patients performed a 7-m back-and-forth walk in a baseline state and with visual and auditory cues. Gait velocity, stride length and cadence were evaluated using a three-dimensional gait analysis system. For speech evaluation, patients read ten sentences in a baseline state and with visual and auditory cues. The time delay of speech initiation, speech rate and the number of repetitions per sentence were quantified. In PDGF patients, the increase in gait velocity positively correlated with the decrease in the time delay of the speech initiation. Also, the increase in the gait velocity and cadence positively correlated with the decrease in the number of repetitions per sentence. The increase in the stride length positively correlated with the increase in speech rate. Lastly, the increase in stride length positively correlated with the decrease in the number of repetitions per sentence. These findings suggest that there is a common pathomechanism of gait freezing and speech disturbance in PD.

AB - Gait freezing and speech disturbance are disabling axial features of Parkinson's disease (PD). However, the pathogenesis of these features remains unclear. We investigated the relation between changes in gait freezing and speech disturbance using visual and auditory cues in PD. 18 PD patients, comprising of 9 patients with freezing (PDGF) and 9 without gait freezing were studied. Patients performed a 7-m back-and-forth walk in a baseline state and with visual and auditory cues. Gait velocity, stride length and cadence were evaluated using a three-dimensional gait analysis system. For speech evaluation, patients read ten sentences in a baseline state and with visual and auditory cues. The time delay of speech initiation, speech rate and the number of repetitions per sentence were quantified. In PDGF patients, the increase in gait velocity positively correlated with the decrease in the time delay of the speech initiation. Also, the increase in the gait velocity and cadence positively correlated with the decrease in the number of repetitions per sentence. The increase in the stride length positively correlated with the increase in speech rate. Lastly, the increase in stride length positively correlated with the decrease in the number of repetitions per sentence. These findings suggest that there is a common pathomechanism of gait freezing and speech disturbance in PD.

KW - Auditory cue

KW - Freezing of gait

KW - Parkinson's disease

KW - Speech

KW - Visual cue

UR - http://www.scopus.com/inward/record.url?scp=84896720147&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896720147&partnerID=8YFLogxK

U2 - 10.1007/s10072-013-1519-1

DO - 10.1007/s10072-013-1519-1

M3 - Article

C2 - 23975521

AN - SCOPUS:84896720147

VL - 35

SP - 357

EP - 363

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

IS - 3

ER -