Gallbladder wall thickening in patients with acute hepatitis

Ki Tae Suk, Chul Han Kim, Soon Koo Baik, Moon Young Kim, Dong Hun Park, Kyu Hong Kim, Jae Woo Kim, Hyun Soo Kim, Sang Ok Kwon, Dong Ki Lee, Kwang Hyup Han, Soon Ho Um

    Research output: Contribution to journalArticlepeer-review

    26 Citations (Scopus)

    Abstract

    Background. Gallbladder wall thickening (GWT) is often observed in patients with acute hepatitis (AH). However, little is known regarding the relationship between AH and GWT. We analyzed the characteristics of GWT in patients with AH. Method. Between April 2002 and April 2007, 232 patients with AH underwent a sonographic examination. The clinical and laboratory findings of patients with GWT were evaluated and compared with patients without GWT. Data were recorded for the following variables: gender, age, laboratory findings, duration of symptom, presence of gallstone, and etiology of GWT. Results. A total of 147 (63%) patients with AH had GWT. GWT in patients with an alanine aminotransferase level more than 500 IU/l (5.2 ± 3.4 mm) was greater than that in other patients (3.9 ± 2.3 mm; p < 0.05). Hepatitis A virus infection (odds ratio 5 3.17 [1.42-7.09]), female gender (odds ratio 5 2.47 [1.34- 4.56]), and an elevated total bilirubin level (odds ratio 5 1.09 [1.03-1.15]) were positively associated with GWT. Conclusion. The incidence of GWT in patients with AH was 63%, and there was an association with hepatitis A virus infection, female gender, and an elevated total bilirubin level.

    Original languageEnglish
    Pages (from-to)144-148
    Number of pages5
    JournalJournal of Clinical Ultrasound
    Volume37
    Issue number3
    DOIs
    Publication statusPublished - 2009 Mar

    Keywords

    • Association
    • Gallbladder
    • Hepatitis
    • Ultrasonography

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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