Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells

Jiho Min, Chang Woo Lee, Man Bock Gu

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalRadiation and Environmental Biophysics
Volume42
Issue number3
DOIs
Publication statusPublished - 2003 Oct
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Radiation
  • Environmental Science(all)

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