TY - JOUR
T1 - Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells
AU - Min, Jiho
AU - Lee, Chang Woo
AU - Gu, Man Bock
N1 - Funding Information:
Acknowledgements The authors are grateful to Dr. In Gyu Kim for the irradiation of the cells and Ms. Hyun Joo Lee for technical assistance in the preparation of the samples. This work was supported by the National Research Laboratory (2001 NRL) program of the Korea Institute of Science and Technology Evaluation and Planning (Project No. M10104000094-01J000004100). The authors are grateful for their support.
PY - 2003/10
Y1 - 2003/10
N2 - In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.
AB - In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.
UR - http://www.scopus.com/inward/record.url?scp=0345166011&partnerID=8YFLogxK
U2 - 10.1007/s00411-003-0205-8
DO - 10.1007/s00411-003-0205-8
M3 - Article
C2 - 13680259
AN - SCOPUS:0345166011
SN - 0301-634X
VL - 42
SP - 189
EP - 192
JO - Radiation and Environmental Biophysics
JF - Radiation and Environmental Biophysics
IS - 3
ER -