Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells

Jiho Min, Chang Woo Lee, Man Bock Gu

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalRadiation and Environmental Biophysics
Volume42
Issue number3
DOIs
Publication statusPublished - 2003 Oct 1
Externally publishedYes

Fingerprint

Gamma Rays
toxicity
Gamma rays
DNA damage
DNA Damage
Dosimetry
gamma radiation
Toxicity
deoxyribonucleic acid
gamma rays
Radiation
damage
DNA
Bacterial DNA
dosage
cells
Escherichia coli
Bacteria
Irradiation
radiation

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biophysics
  • Environmental Science(all)
  • Environmental Chemistry
  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells. / Min, Jiho; Lee, Chang Woo; Gu, Man Bock.

In: Radiation and Environmental Biophysics, Vol. 42, No. 3, 01.10.2003, p. 189-192.

Research output: Contribution to journalArticle

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