TY - JOUR
T1 - Gender differences in the presentation of chest pain in obstructive coronary artery disease
T2 - Results from the korean women’s chest pain registry
AU - Cho, Dong Hyuk
AU - Choi, Jimi
AU - Kim, Mi Na
AU - Kim, Hack Lyoung
AU - Kim, Yong Hyun
AU - Na, Jin Oh
AU - Jeong, Jin Ok
AU - Yoon, Hyun Ju
AU - Shin, Mi Seung
AU - Kim, Myung A.
AU - Hong, Kyung Soon
AU - Shin, Gil Ja
AU - Park, Seong Mi
AU - Shim, Wan Joo
N1 - Publisher Copyright:
© 2020 The Korean Association of Internal Medicine.
PY - 2020/5
Y1 - 2020/5
N2 - Background/Aims: Chest pain in patients with obstructive coronary artery disease (OCAD) is affected by several social factors. The gender-based differences in chest pain among Koreans have yet to be investigated. Methods: The study consecutively enrolled 1,549 patients (male/female, 514/1,035; 61 ± 11 years old) with suspected angina. The predictive factors for OCAD based on gender were evaluated. Results: Men experienced more squeezing type pain on the left side of chest, while women demonstrated more dull quality pain in the retrosternal and epi-gastric area. After adjustment for risk factors, pain in the retrosternal area (odds ratio [OR], 1. 491; 95% confidence interval [CI], 1.178 to 1.887) and aggravation by exercise (OR, 2.235; 95% CI, 1.745 to 2.861) were positively associated with OCAD. In men, shorter duration (OR, 1.581; 95% CI, 1.086 to 2.303) and dyspnea (OR, 1.610; 95% CI, 1.040 to 2. 490) increased the probability for OCAD, while left-sid-ed chest pain suggested a low probability for OCAD (OR, 0.590; 95% CI, 0.388 to 0.897). In women, aggravation by emotional stress (OR, 0.348; 95% CI, 0.162 to 0.746) and dizziness (OR, 0. 457; 95% CI, 0.246 to 0.849) decreased the probability for OCAD. Conclusions: This is the first study to focus on gender differences in chest pain among Koreans with angina. Symptoms with high probability for OCAD were different between sexes. Our findings suggest that patient’s medical history in pretest assessment for OCAD should be individualized considering gender.
AB - Background/Aims: Chest pain in patients with obstructive coronary artery disease (OCAD) is affected by several social factors. The gender-based differences in chest pain among Koreans have yet to be investigated. Methods: The study consecutively enrolled 1,549 patients (male/female, 514/1,035; 61 ± 11 years old) with suspected angina. The predictive factors for OCAD based on gender were evaluated. Results: Men experienced more squeezing type pain on the left side of chest, while women demonstrated more dull quality pain in the retrosternal and epi-gastric area. After adjustment for risk factors, pain in the retrosternal area (odds ratio [OR], 1. 491; 95% confidence interval [CI], 1.178 to 1.887) and aggravation by exercise (OR, 2.235; 95% CI, 1.745 to 2.861) were positively associated with OCAD. In men, shorter duration (OR, 1.581; 95% CI, 1.086 to 2.303) and dyspnea (OR, 1.610; 95% CI, 1.040 to 2. 490) increased the probability for OCAD, while left-sid-ed chest pain suggested a low probability for OCAD (OR, 0.590; 95% CI, 0.388 to 0.897). In women, aggravation by emotional stress (OR, 0.348; 95% CI, 0.162 to 0.746) and dizziness (OR, 0. 457; 95% CI, 0.246 to 0.849) decreased the probability for OCAD. Conclusions: This is the first study to focus on gender differences in chest pain among Koreans with angina. Symptoms with high probability for OCAD were different between sexes. Our findings suggest that patient’s medical history in pretest assessment for OCAD should be individualized considering gender.
KW - Angina pectoris
KW - Chest pain
KW - Coronary artery disease
KW - Sex characteristics
UR - http://www.scopus.com/inward/record.url?scp=85077163686&partnerID=8YFLogxK
U2 - 10.3904/kjim.2018.320
DO - 10.3904/kjim.2018.320
M3 - Article
C2 - 30879289
AN - SCOPUS:85077163686
VL - 35
SP - 582
EP - 592
JO - Korean Journal of Internal Medicine
JF - Korean Journal of Internal Medicine
SN - 0494-4712
IS - 3
ER -