Abstract
The present study reports an innovative way to produce large pore channels with a size >100 μm for applications in bone tissue engineering using the camphene-based freeze casting method, and using an unusually high freezing temperature, which is close to the solidification temperature of the slurry, in order to allow the formation of excessively overgrown camphene dendrites due to the extremely low solidification velocity. To accomplish this, hydroxyapatite (HA)/slurries with various solid loadings (10, 15, and 20 vol%) were frozen at 35°C for 20 h. The frozen samples were freeze dried and sintered at 1250°C for 3 h. All of the fabricated samples showed highly porous structures with large pore channels >100 μm in size and dense HA walls without any noticeable defects, such as cracks or pores. As the initial solid loading was increased from 10 to 20 vol%, the porosity of the sample decreased linearly from 76% to 55%, while the pore channels became narrower. However, the compressive strength was remarkably improved from 2.5 to 16.7 MPa.
| Original language | English |
|---|---|
| Pages (from-to) | 1744-1752 |
| Number of pages | 9 |
| Journal | Journal of the American Ceramic Society |
| Volume | 90 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2007 Jun 1 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ceramics and Composites
Cite this
Generation of large pore channels for bone tissue engineering using camphene-based freeze casting. / Yoon, Byung Ho; Koh, Young-Hag; Park, Chee Sung; Kim, Hyoun Ee.
In: Journal of the American Ceramic Society, Vol. 90, No. 6, 01.06.2007, p. 1744-1752.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Generation of large pore channels for bone tissue engineering using camphene-based freeze casting
AU - Yoon, Byung Ho
AU - Koh, Young-Hag
AU - Park, Chee Sung
AU - Kim, Hyoun Ee
PY - 2007/6/1
Y1 - 2007/6/1
N2 - The present study reports an innovative way to produce large pore channels with a size >100 μm for applications in bone tissue engineering using the camphene-based freeze casting method, and using an unusually high freezing temperature, which is close to the solidification temperature of the slurry, in order to allow the formation of excessively overgrown camphene dendrites due to the extremely low solidification velocity. To accomplish this, hydroxyapatite (HA)/slurries with various solid loadings (10, 15, and 20 vol%) were frozen at 35°C for 20 h. The frozen samples were freeze dried and sintered at 1250°C for 3 h. All of the fabricated samples showed highly porous structures with large pore channels >100 μm in size and dense HA walls without any noticeable defects, such as cracks or pores. As the initial solid loading was increased from 10 to 20 vol%, the porosity of the sample decreased linearly from 76% to 55%, while the pore channels became narrower. However, the compressive strength was remarkably improved from 2.5 to 16.7 MPa.
AB - The present study reports an innovative way to produce large pore channels with a size >100 μm for applications in bone tissue engineering using the camphene-based freeze casting method, and using an unusually high freezing temperature, which is close to the solidification temperature of the slurry, in order to allow the formation of excessively overgrown camphene dendrites due to the extremely low solidification velocity. To accomplish this, hydroxyapatite (HA)/slurries with various solid loadings (10, 15, and 20 vol%) were frozen at 35°C for 20 h. The frozen samples were freeze dried and sintered at 1250°C for 3 h. All of the fabricated samples showed highly porous structures with large pore channels >100 μm in size and dense HA walls without any noticeable defects, such as cracks or pores. As the initial solid loading was increased from 10 to 20 vol%, the porosity of the sample decreased linearly from 76% to 55%, while the pore channels became narrower. However, the compressive strength was remarkably improved from 2.5 to 16.7 MPa.
UR - http://www.scopus.com/inward/record.url?scp=34249862774&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249862774&partnerID=8YFLogxK
U2 - 10.1111/j.1551-2916.2007.01670.x
DO - 10.1111/j.1551-2916.2007.01670.x
M3 - Article
AN - SCOPUS:34249862774
VL - 90
SP - 1744
EP - 1752
JO - Journal of the American Ceramic Society
JF - Journal of the American Ceramic Society
SN - 0002-7820
IS - 6
ER -