Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary

Hae Ji Kang, Satoru Arai, Andrew G. Hope, Jin Won Song, Joseph A. Cook, Richard Yanagihara

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.

Original languageEnglish
Article number208
JournalVirology Journal
Volume6
DOIs
Publication statusPublished - 2009 Dec 1

Fingerprint

Shrews
Phylogeography
Hantavirus
Hungary
Finland
Viruses
Bayes Theorem
RNA Viruses
Russia
Switzerland
Reverse Transcription
Rodentia
RNA
Antigens
Polymerase Chain Reaction
Liver

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary. / Kang, Hae Ji; Arai, Satoru; Hope, Andrew G.; Song, Jin Won; Cook, Joseph A.; Yanagihara, Richard.

In: Virology Journal, Vol. 6, 208, 01.12.2009.

Research output: Contribution to journalArticle

Kang, Hae Ji ; Arai, Satoru ; Hope, Andrew G. ; Song, Jin Won ; Cook, Joseph A. ; Yanagihara, Richard. / Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary. In: Virology Journal. 2009 ; Vol. 6.
@article{2bb7d3b7052b4a88be956c1c2f3d4cfe,
title = "Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary",
abstract = "Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5{\%}) and 13 of 66 (19.7{\%}) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.",
author = "Kang, {Hae Ji} and Satoru Arai and Hope, {Andrew G.} and Song, {Jin Won} and Cook, {Joseph A.} and Richard Yanagihara",
year = "2009",
month = "12",
day = "1",
doi = "10.1186/1743-422X-6-208",
language = "English",
volume = "6",
journal = "Virology Journal",
issn = "1743-422X",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary

AU - Kang, Hae Ji

AU - Arai, Satoru

AU - Hope, Andrew G.

AU - Song, Jin Won

AU - Cook, Joseph A.

AU - Yanagihara, Richard

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.

AB - Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.

UR - http://www.scopus.com/inward/record.url?scp=72849120929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=72849120929&partnerID=8YFLogxK

U2 - 10.1186/1743-422X-6-208

DO - 10.1186/1743-422X-6-208

M3 - Article

C2 - 19930716

AN - SCOPUS:72849120929

VL - 6

JO - Virology Journal

JF - Virology Journal

SN - 1743-422X

M1 - 208

ER -