TY - JOUR
T1 - Genetic diversity and phylogeography of seewis virus in the Eurasian common shrew in Finland and Hungary
AU - Kang, Hae Ji
AU - Arai, Satoru
AU - Hope, Andrew G.
AU - Song, Jin Won
AU - Cook, Joseph A.
AU - Yanagihara, Richard
N1 - Funding Information:
Dr. Duane A. Schlitter and Dr. Gabor R. Racz collected the shrew tissues in Finland and Hungary, respectively. Ms. Laarni Sumibcay provided technical assistance. This work was supported in part by U.S. Public Health Service grants R01AI075057 from the National Institute of Allergy and Infectious Diseases, and P20RR018727 (Centers of Biomedical Research Excellence) and G12RR003061 (Research Centers in Minority Institutions) from the National Center for Research Resources, National Institutes of Health.
PY - 2009
Y1 - 2009
N2 - Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.
AB - Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.
UR - http://www.scopus.com/inward/record.url?scp=72849120929&partnerID=8YFLogxK
U2 - 10.1186/1743-422X-6-208
DO - 10.1186/1743-422X-6-208
M3 - Article
C2 - 19930716
AN - SCOPUS:72849120929
VL - 6
JO - Virology Journal
JF - Virology Journal
SN - 1743-422X
M1 - 208
ER -
