Giant melanotrichoblastoma

Deok-Woo Kim, Jeong Hyeon Lee, Insun Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Trichoblastomas are benign skin tumors composed mostly of follicular germinative cells recapitulating the differentiation of hair follicles. Several variants of trichoblastomas have been reported, including pigmented trichoblastomas, melanotrichoblastomas, subcutaneous trichoblastomas, or giant trichoblastomas. We report a rare case of a pigmented trichoblastoma with abundant dendritic melanocytes. A 51-year-old Korean man had a round soft tissue mass on his back. The tumor was 6 cm in size and located in the subcutaneous fatty layer. On immunohistochemical stain for Melan A, numerous dendritic melanocytes were demonstrated in both pigmented and nonpigmented epithelial cell components. These cells were also positive for HMB45, and some of the dendritic melanocytes were positive for S-100 protein. With the aid of immunohistochemical staining, we diagnosed the tumor as a giant melanotrichoblastoma.

Original languageEnglish
JournalAmerican Journal of Dermatopathology
Volume33
Issue number3
DOIs
Publication statusPublished - 2011 May 1

Fingerprint

Melanocytes
MART-1 Antigen
Neoplasms
Hair Follicle
S100 Proteins
Cellular Structures
Cell Differentiation
Coloring Agents
Epithelial Cells
Staining and Labeling
Skin

Keywords

  • giant trichoblastoma
  • melanotrichoblastoma
  • pigmented trichoblastoma
  • trichoblastoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

Giant melanotrichoblastoma. / Kim, Deok-Woo; Lee, Jeong Hyeon; Kim, Insun.

In: American Journal of Dermatopathology, Vol. 33, No. 3, 01.05.2011.

Research output: Contribution to journalArticle

Kim, Deok-Woo ; Lee, Jeong Hyeon ; Kim, Insun. / Giant melanotrichoblastoma. In: American Journal of Dermatopathology. 2011 ; Vol. 33, No. 3.
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