Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

Jung Woo Choi; Youngseok Lee; Jung Suk An; Nam Hee Won; Yong Gu Chung; Yang Seok Chae

Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

Jung Woo Choi, Youngseok Lee, Jung Suk An, Nam Hee Won, Yong Gu Chung, Yang Seok Chae

Research output: Contribution to journal › Article › peer-review

Abstract

Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.

Original language	English
Pages (from-to)	45-49
Number of pages	5
Journal	Korean Journal of Pathology
Volume	42
Issue number	1
Publication status	Published - 2008

Keywords

Anaplastic oligodendroglioma
CD34
Gliosarcoma
S-100 protein

ASJC Scopus subject areas

Pathology and Forensic Medicine

Cite this

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title = "Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report",

abstract = "Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.",

keywords = "Anaplastic oligodendroglioma, CD34, Gliosarcoma, S-100 protein",

author = "Choi, {Jung Woo} and Youngseok Lee and An, {Jung Suk} and Won, {Nam Hee} and Chung, {Yong Gu} and Chae, {Yang Seok}",

year = "2008",

language = "English",

volume = "42",

pages = "45--49",

journal = "Journal of Pathology and Translational Medicine",

issn = "2383-7837",

publisher = "Korean Society of Pathologists",

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TY - JOUR

T1 - Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

AU - Choi, Jung Woo

AU - Lee, Youngseok

AU - An, Jung Suk

AU - Won, Nam Hee

AU - Chung, Yong Gu

AU - Chae, Yang Seok

PY - 2008

Y1 - 2008

N2 - Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.

AB - Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.

KW - Anaplastic oligodendroglioma

KW - CD34

KW - Gliosarcoma

KW - S-100 protein

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M3 - Article

AN - SCOPUS:59849129865

VL - 42

SP - 45

EP - 49

JO - Journal of Pathology and Translational Medicine

JF - Journal of Pathology and Translational Medicine

SN - 2383-7837

IS - 1

ER -

Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

Abstract

Keywords

ASJC Scopus subject areas

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