Abstract
Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.
| Original language | English |
|---|---|
| Pages (from-to) | 45-49 |
| Number of pages | 5 |
| Journal | Korean Journal of Pathology |
| Volume | 42 |
| Issue number | 1 |
| Publication status | Published - 2008 Dec 1 |
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Keywords
- Anaplastic oligodendroglioma
- CD34
- Gliosarcoma
- S-100 protein
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report. / Choi, Jung-Woo; Lee, Youngseok; An, Jung Suk; Won, Nam Hee; Chung, Yong Gu; Chae, Yang Seok.
In: Korean Journal of Pathology, Vol. 42, No. 1, 01.12.2008, p. 45-49.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report
AU - Choi, Jung-Woo
AU - Lee, Youngseok
AU - An, Jung Suk
AU - Won, Nam Hee
AU - Chung, Yong Gu
AU - Chae, Yang Seok
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.
AB - Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.
KW - Anaplastic oligodendroglioma
KW - CD34
KW - Gliosarcoma
KW - S-100 protein
UR - http://www.scopus.com/inward/record.url?scp=59849129865&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=59849129865&partnerID=8YFLogxK
M3 - Article
VL - 42
SP - 45
EP - 49
JO - Journal of Pathology and Translational Medicine
JF - Journal of Pathology and Translational Medicine
SN - 2383-7837
IS - 1
ER -