Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

Jung-Woo Choi, Youngseok Lee, Jung Suk An, Nam Hee Won, Yong Gu Chung, Yang Seok Chae

Research output: Contribution to journalArticle

Abstract

Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalKorean Journal of Pathology
Volume42
Issue number1
Publication statusPublished - 2008 Dec 1

Fingerprint

Gliosarcoma
Oligodendroglioma
S100 Proteins
Peripheral Nerves
Neuroglia
Neoplasms
Stem Cells

Keywords

  • Anaplastic oligodendroglioma
  • CD34
  • Gliosarcoma
  • S-100 protein

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report. / Choi, Jung-Woo; Lee, Youngseok; An, Jung Suk; Won, Nam Hee; Chung, Yong Gu; Chae, Yang Seok.

In: Korean Journal of Pathology, Vol. 42, No. 1, 01.12.2008, p. 45-49.

Research output: Contribution to journalArticle

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