Gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells - A case report

Jung Woo Choi, Youngseok Lee, Jung Suk An, Nam Hee Won, Yong Gu Chung, Yang Seok Chae

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendrogliomia and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.

    Original languageEnglish
    Pages (from-to)45-49
    Number of pages5
    JournalKorean Journal of Pathology
    Volume42
    Issue number1
    Publication statusPublished - 2008

    Keywords

    • Anaplastic oligodendroglioma
    • CD34
    • Gliosarcoma
    • S-100 protein

    ASJC Scopus subject areas

    • Pathology and Forensic Medicine

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