Gold nanocrystals with DNA-directed morphologies

Xingyi Ma, June Huh, Wounjhang Park, Luke P. Lee, Young Jik Kwon, Sang Jun Sim

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Precise control over the structure of metal nanomaterials is important for developing advanced nanobiotechnology. Assembly methods of nanoparticles into structured blocks have been widely demonstrated recently. However, synthesis of nanocrystals with controlled, three-dimensional structures remains challenging. Here we show a directed crystallization of gold by a single DNA molecular regulator in a sequence-independent manner and its applications in three-dimensional topological controls of crystalline nanostructures. We anchor DNA onto gold nanoseed with various alignments to form gold nanocrystals with defined topologies. Some topologies are asymmetric including pushpin-, star-and biconcave disk-like structures, as well as more complex jellyfish-and flower-like structures. The approach of employing DNA enables the solution-based synthesis of nanocrystals with controlled, three-dimensional structures in a desired direction, and expands the current tools available for designing and synthesizing feature-rich nanomaterials for future translational biotechnology.

Original languageEnglish
Article number12873
JournalNature Communications
Volume7
DOIs
Publication statusPublished - 2016 Sep 16

Fingerprint

Gold
Nanoparticles
Nanocrystals
Nanostructures
nanocrystals
deoxyribonucleic acid
gold
Nanostructured materials
DNA
topology
Nanobiotechnology
Topology
biotechnology
regulators
synthesis
Biotechnology
Crystallization
Anchors
Stars
assembly

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

Cite this

Gold nanocrystals with DNA-directed morphologies. / Ma, Xingyi; Huh, June; Park, Wounjhang; Lee, Luke P.; Kwon, Young Jik; Sim, Sang Jun.

In: Nature Communications, Vol. 7, 12873, 16.09.2016.

Research output: Contribution to journalArticle

Ma, Xingyi ; Huh, June ; Park, Wounjhang ; Lee, Luke P. ; Kwon, Young Jik ; Sim, Sang Jun. / Gold nanocrystals with DNA-directed morphologies. In: Nature Communications. 2016 ; Vol. 7.
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