Gold nanoparticles - Based colorimetric single nucleotide polymorphisms genotyping utilizing allele-specific PCR

Ye Lim Jung, Cheulhee Jung, Harshala Parab, Hyun Gyu Park

Research output: Contribution to journalArticle

Abstract

A very convenient colorimetric method for the identification of single nucleotide polymorphism was developed utilizing gold nanoparticles and an allele-specific polymerase chain reaction and its diagnostic capability was successfully verified by correctly identifying various mutations in the BRCA1 gene.

Original languageEnglish
Pages (from-to)1062-1065
Number of pages4
JournalIFMBE Proceedings
Volume37
DOIs
Publication statusPublished - 2011 Nov 9
Externally publishedYes

Keywords

  • allelespecific PCR
  • BRCA
  • gold nanoparticles
  • Single nucleotide polymorphism (SNP)
  • thiolated primer

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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