Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion

Mi Ri Kim; Seungwoo Lee; Jung Ki Park; Kuk Young Cho

doi:10.1039/c0cc01738h

Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion

Mi Ri Kim, Seungwoo Lee, Jung Ki Park, Kuk Young Cho

KU-KIST Graduate School of Converging Science and Technology

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Simple oil-in-water emulsion led to structural complexity at both the surface and interior of the PLGA microsphere. A golf ball-like dimpled surface comes from the heteroaggregation of volatile nonsolvent colloid originating from the inside of the organic droplet as supported by in situ optical microscopy. The internal porous structure and encapsulation of hydrophobic agent inside the microparticle implies its potential application as a drug carrier.

Original language	English
Pages (from-to)	7433-7435
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	39
DOIs	https://doi.org/10.1039/c0cc01738h
Publication status	Published - 2010 Oct 21

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c0cc01738h

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abstract = "Simple oil-in-water emulsion led to structural complexity at both the surface and interior of the PLGA microsphere. A golf ball-like dimpled surface comes from the heteroaggregation of volatile nonsolvent colloid originating from the inside of the organic droplet as supported by in situ optical microscopy. The internal porous structure and encapsulation of hydrophobic agent inside the microparticle implies its potential application as a drug carrier.",

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AB - Simple oil-in-water emulsion led to structural complexity at both the surface and interior of the PLGA microsphere. A golf ball-like dimpled surface comes from the heteroaggregation of volatile nonsolvent colloid originating from the inside of the organic droplet as supported by in situ optical microscopy. The internal porous structure and encapsulation of hydrophobic agent inside the microparticle implies its potential application as a drug carrier.

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Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion

Abstract

ASJC Scopus subject areas

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