Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion

Mi Ri Kim, Seungwoo Lee, Jung Ki Park, Kuk Young Cho

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Simple oil-in-water emulsion led to structural complexity at both the surface and interior of the PLGA microsphere. A golf ball-like dimpled surface comes from the heteroaggregation of volatile nonsolvent colloid originating from the inside of the organic droplet as supported by in situ optical microscopy. The internal porous structure and encapsulation of hydrophobic agent inside the microparticle implies its potential application as a drug carrier.

Original languageEnglish
Pages (from-to)7433-7435
Number of pages3
JournalChemical Communications
Volume46
Issue number39
DOIs
Publication statusPublished - 2010 Oct 21

Fingerprint

Golf
Drug Carriers
Colloids
Emulsions
Microspheres
Microscopy
Oils
Water
Encapsulation
Optical microscopy
polylactic acid-polyglycolic acid copolymer

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion. / Kim, Mi Ri; Lee, Seungwoo; Park, Jung Ki; Cho, Kuk Young.

In: Chemical Communications, Vol. 46, No. 39, 21.10.2010, p. 7433-7435.

Research output: Contribution to journalArticle

Kim, Mi Ri ; Lee, Seungwoo ; Park, Jung Ki ; Cho, Kuk Young. / Golf ball-shaped PLGA microparticles with internal pores fabricated by simple O/W emulsion. In: Chemical Communications. 2010 ; Vol. 46, No. 39. pp. 7433-7435.
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