Graphical models and inference on graphs in genomics: Challenges of high-throughput data analysis

Manohar Shamaiah; Sang Hyun Lee; Haris Vikalo

doi:10.1109/MSP.2011.943012

Graphical models and inference on graphs in genomics: Challenges of high-throughput data analysis

Manohar Shamaiah, Sang Hyun Lee, Haris Vikalo

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Recent technological advances in high-throughput molecular screening and DNA sequencing have enabled acquisition of enormous amounts of biological data that may provide critical information about the functionality of cells and organisms [1], help reveal mechanisms of genetic diseases and disorders [2], improve the efficiency of the drug discovery process [3], and enable development of diagnostic techniques and therapies [4]. Novel sequencing methods allow fast and affordable deciphering of individual genomes and thus enable studies of genetic variations and the effects they have on human health and medical treatments.

Original language	English
Article number	6105453
Pages (from-to)	51-65
Number of pages	15
Journal	IEEE Signal Processing Magazine
Volume	29
Issue number	1
DOIs	https://doi.org/10.1109/MSP.2011.943012
Publication status	Published - 2012 Jan
Externally published	Yes

ASJC Scopus subject areas

Signal Processing
Electrical and Electronic Engineering
Applied Mathematics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/MSP.2011.943012

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abstract = "Recent technological advances in high-throughput molecular screening and DNA sequencing have enabled acquisition of enormous amounts of biological data that may provide critical information about the functionality of cells and organisms [1], help reveal mechanisms of genetic diseases and disorders [2], improve the efficiency of the drug discovery process [3], and enable development of diagnostic techniques and therapies [4]. Novel sequencing methods allow fast and affordable deciphering of individual genomes and thus enable studies of genetic variations and the effects they have on human health and medical treatments.",

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Graphical models and inference on graphs in genomics: Challenges of high-throughput data analysis

Abstract

ASJC Scopus subject areas

UN SDGs

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