Groupwise registration of breast DCE-MR images for accurate tumor measurement

Minjeong Kim, Guorong Wu, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

The registration of breast DCE-MR images can help correct possible motions during image acquisition, and is also important for diagnosis of breast cancer, i.e., discrimination between benign and malignant tumors. However, deformable registration of DCE-MR images is challenging due to drastic image contrast change over time (especially between pre- and post-contrast images). To improve the registration, we propose a novel hierarchical groupwise registration framework by specially considering the image characteristics of the breast DCE-MR images. Specifically, due to the similarity of post-contrast images, they are jointly registered by a groupwise registration method, and then registered together with the pre-contrast image by a robust correspondence detection technique based on local-steering-kernel features, instead of simple image intensities. Also, to accurately register the tumor region, we treat the motion in tumor area and other normal tissues differently by delineating rigid motion for tumor while non-rigid for other normal tissues. Our experimental results on both real and simulated images show that our method can achieve more consistent and accurate registration results than the conventional pairwise registration method.

Original languageEnglish
Title of host publicationProceedings - International Symposium on Biomedical Imaging
Pages598-601
Number of pages4
DOIs
Publication statusPublished - 2011 Nov 2
Externally publishedYes
Event2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11 - Chicago, IL, United States
Duration: 2011 Mar 302011 Apr 2

Other

Other2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
CountryUnited States
CityChicago, IL
Period11/3/3011/4/2

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Keywords

  • Dynamic contrast-enhanced breast MRI
  • Groupwise registration
  • Local steering kernel

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Kim, M., Wu, G., & Shen, D. (2011). Groupwise registration of breast DCE-MR images for accurate tumor measurement. In Proceedings - International Symposium on Biomedical Imaging (pp. 598-601). [5872478] https://doi.org/10.1109/ISBI.2011.5872478