Gyral net: A new representation of cortical folding organization

Hanbo Chen, Yujie Li, Fangfei Ge, Gang Li, Dinggang Shen, Tianming Liu

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

One distinct feature of the cerebral cortex is its convex (gyri) and concave (sulci) folding patterns. Due to the remarkable complexity and variability of gyral/sulcal shapes, it has been challenging to quantitatively model their organization patterns. Inspired by the observation that the lines of gyral crests can form a connected graph on each brain hemisphere, we propose a new representation of cortical gyri/sulci organization pattern – gyral net, which models cortical architecture from a graph perspective, starting with nodes and edges obtained from the reconstructed cortical surfaces. A novel computational framework is developed to efficiently and automatically construct gyral nets from surface meshes, and four measurements are devised to quantify the folding patterns. Using an MRI dataset for autism study as a test bed, we identified reduced local connectivity cost and increased curviness of gyral net bilaterally on the parietal lobe, occipital lobe, and temporal lobe in autistic patients. Additionally, we found that the cortical thickness and the gyral straightness of gyral joints are higher than the rest of gyral crest regions. The proposed representation offers a new tool for a comprehensive and reliable characterization of the cortical folding organization. This novel computational framework will enable large-scale analyses of cortical folding patterns in the future.

Original languageEnglish
Pages (from-to)14-25
Number of pages12
JournalMedical Image Analysis
Volume42
DOIs
Publication statusPublished - 2017 Dec 1

Fingerprint

Organizations
Occipital Lobe
Parietal Lobe
Temporal Lobe
Autistic Disorder
Cerebral Cortex
Magnetic resonance imaging
Brain
Joints
Costs and Cost Analysis
Costs
Datasets

Keywords

  • Autism
  • Cortical folding
  • Gyral net
  • MRI

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design

Cite this

Gyral net : A new representation of cortical folding organization. / Chen, Hanbo; Li, Yujie; Ge, Fangfei; Li, Gang; Shen, Dinggang; Liu, Tianming.

In: Medical Image Analysis, Vol. 42, 01.12.2017, p. 14-25.

Research output: Contribution to journalArticle

Chen, Hanbo ; Li, Yujie ; Ge, Fangfei ; Li, Gang ; Shen, Dinggang ; Liu, Tianming. / Gyral net : A new representation of cortical folding organization. In: Medical Image Analysis. 2017 ; Vol. 42. pp. 14-25.
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