Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump

Choon Hak Lim, Ho Sung Son, Yung Hu Fang, Jung Joo Lee, Kwang Je Baik, Kyung Hyun Kim, Bum Soo Kim, Hye Won Lee, Kyung Sun

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    21 Citations (Scopus)

    Abstract

    We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE).In five cardiac-arrested pigs, the outflow cannula of the CP was inserted into the ascending aorta, the inflow cannula in the right atrium. A 30-ml IABP was subsequently placed in the descending aorta. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg per minute by CP alone or by IABP/CP with pressure and flow measured in the right internal carotid artery.The IABP/CP combination converted the flow to pulsatile and increased pulse pressure significantly from 9.1 ± 1.3 mm Hg to 54.9 ± 6.1 mm Hg (p = 0.012). It also significantly increased the percent change from mean arterial pressure to EEP from 0.2 ± 0.3% to 23.3 ± 6.1% (p = 0.012) and SHE from 133.2 ± 234.5 erg/cm to 20,219.8 ± 5842.7 erg/cm (p = 0.012). However, no statistical difference was observed between CP and IABP/CP in terms of mean carotid artery pressure (p = NS).In a cardiac-arrested animal model, pulsatility generated by a IABP/CP combination may be effective in terms of energy equivalent pressure and surplus hemodynamic energy.

    Original languageEnglish
    Pages (from-to)592-594
    Number of pages3
    JournalASAIO Journal
    Volume52
    Issue number5
    DOIs
    Publication statusPublished - 2006 Sep

    ASJC Scopus subject areas

    • Biophysics
    • Bioengineering
    • Biomaterials
    • Biomedical Engineering

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