Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump

Choon Hak Lim, Ho Sung Son, Yung Hu Fang, Jung Joo Lee, Kwang Je Baik, Kyung Hyun Kim, Bum Soo Kim, Hye Won Lee, Kyung Sun

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE).In five cardiac-arrested pigs, the outflow cannula of the CP was inserted into the ascending aorta, the inflow cannula in the right atrium. A 30-ml IABP was subsequently placed in the descending aorta. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg per minute by CP alone or by IABP/CP with pressure and flow measured in the right internal carotid artery.The IABP/CP combination converted the flow to pulsatile and increased pulse pressure significantly from 9.1 ± 1.3 mm Hg to 54.9 ± 6.1 mm Hg (p = 0.012). It also significantly increased the percent change from mean arterial pressure to EEP from 0.2 ± 0.3% to 23.3 ± 6.1% (p = 0.012) and SHE from 133.2 ± 234.5 erg/cm to 20,219.8 ± 5842.7 erg/cm (p = 0.012). However, no statistical difference was observed between CP and IABP/CP in terms of mean carotid artery pressure (p = NS).In a cardiac-arrested animal model, pulsatility generated by a IABP/CP combination may be effective in terms of energy equivalent pressure and surplus hemodynamic energy.

Original languageEnglish
Pages (from-to)592-594
Number of pages3
JournalASAIO Journal
Volume52
Issue number5
DOIs
Publication statusPublished - 2006 Sep 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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