Hemophagocytic syndrome in a patient with acute tubulointerstitial nephritis secondary to hepatitis a virus infection

Eunjung Cho, Inhye Cha, Kichul Yoon, Ha Na Yang, Hye Won Kim, Myung-Gyu Kim, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered.

Original languageEnglish
Pages (from-to)1529-1531
Number of pages3
JournalJournal of Korean Medical Science
Volume25
Issue number10
DOIs
Publication statusPublished - 2010 Oct 1

Fingerprint

Hemophagocytic Lymphohistiocytosis
Hepatitis A virus
Hepatitis Viruses
Virus Diseases
Acute Kidney Injury
Viruses
Renal Dialysis
Dialysis
Macrophages
Steroids
T-Lymphocytes
Kidney
Biopsy
Infection
Acute Tubulointerstitial Nephritis
Therapeutics

Keywords

  • Acute hepatitis A
  • Acute kidney injury
  • Hemophagocytic
  • Lymphohistiocytosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hemophagocytic syndrome in a patient with acute tubulointerstitial nephritis secondary to hepatitis a virus infection. / Cho, Eunjung; Cha, Inhye; Yoon, Kichul; Yang, Ha Na; Kim, Hye Won; Kim, Myung-Gyu; Jo, Sang Kyung; Cho, Won Yong; Kim, Hyoung Kyu.

In: Journal of Korean Medical Science, Vol. 25, No. 10, 01.10.2010, p. 1529-1531.

Research output: Contribution to journalArticle

Cho, Eunjung ; Cha, Inhye ; Yoon, Kichul ; Yang, Ha Na ; Kim, Hye Won ; Kim, Myung-Gyu ; Jo, Sang Kyung ; Cho, Won Yong ; Kim, Hyoung Kyu. / Hemophagocytic syndrome in a patient with acute tubulointerstitial nephritis secondary to hepatitis a virus infection. In: Journal of Korean Medical Science. 2010 ; Vol. 25, No. 10. pp. 1529-1531.
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