Hemophagocytic syndrome in a patient with acute tubulointerstitial nephritis secondary to hepatitis a virus infection

Eunjung Cho, Inhye Cha, Kichul Yoon, Ha Na Yang, Hye Won Kim, Myung-Gyu Kim, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)


Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered.

Original languageEnglish
Pages (from-to)1529-1531
Number of pages3
JournalJournal of Korean Medical Science
Issue number10
Publication statusPublished - 2010 Oct 1



  • Acute hepatitis A
  • Acute kidney injury
  • Hemophagocytic
  • Lymphohistiocytosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this