Hemorheological changes caused by lead exposure

C. B. Kim, Sehyun Shin, Seok Heung Song

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalClinical Hemorheology and Microcirculation
Volume55
Issue number3
DOIs
Publication statusPublished - 2013

Keywords

  • Aggregation
  • Deformability
  • Hemorheology
  • Lead
  • Toxicology

ASJC Scopus subject areas

  • Physiology
  • Hematology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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