Hemorheological changes caused by lead exposure

C. B. Kim; Sehyun Shin; Seok Heung Song

doi:10.3233/CH-2012-1641

Hemorheological changes caused by lead exposure

C. B. Kim, Sehyun Shin, Seok Heung Song

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.

Original language	English
Pages (from-to)	341-348
Number of pages	8
Journal	Clinical Hemorheology and Microcirculation
Volume	55
Issue number	3
DOIs	https://doi.org/10.3233/CH-2012-1641
Publication status	Published - 2013

Keywords

Aggregation
Deformability
Hemorheology
Lead
Toxicology

ASJC Scopus subject areas

Physiology
Hematology
Cardiology and Cardiovascular Medicine
Physiology (medical)

Access to Document

10.3233/CH-2012-1641

Fingerprint Dive into the research topics of 'Hemorheological changes caused by lead exposure'. Together they form a unique fingerprint.

Cite this

@article{31437838f73041fd838e3b0e8f7754a2,

title = "Hemorheological changes caused by lead exposure",

abstract = "Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.",

keywords = "Aggregation, Deformability, Hemorheology, Lead, Toxicology",

author = "Kim, {C. B.} and Sehyun Shin and Song, {Seok Heung}",

year = "2013",

doi = "10.3233/CH-2012-1641",

language = "English",

volume = "55",

pages = "341--348",

journal = "Clinical Hemorheology and Microcirculation",

issn = "1386-0291",

publisher = "IOS Press",

number = "3",

}

TY - JOUR

T1 - Hemorheological changes caused by lead exposure

AU - Kim, C. B.

AU - Shin, Sehyun

AU - Song, Seok Heung

PY - 2013

Y1 - 2013

N2 - Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.

AB - Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.

KW - Aggregation

KW - Deformability

KW - Hemorheology

KW - Lead

KW - Toxicology

UR - http://www.scopus.com/inward/record.url?scp=84891079141&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891079141&partnerID=8YFLogxK

U2 - 10.3233/CH-2012-1641

DO - 10.3233/CH-2012-1641

M3 - Article

C2 - 23076008

AN - SCOPUS:84891079141

VL - 55

SP - 341

EP - 348

JO - Clinical Hemorheology and Microcirculation

JF - Clinical Hemorheology and Microcirculation

SN - 1386-0291

IS - 3

ER -

Hemorheological changes caused by lead exposure

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this