Heparin-Coated gold nanopartieles for liver-Specific CT imaging

In Cheol Sun, Dae Kyung Eun, Jin Hee Na, Seulki Lee, I. I Jin Kim, In Chan Youn, Chang Yong Ko, Han Sung Kim, Dohyung Lim, Kuiwon Choi, Phillip B. Messersmith, Tae Gwan Park, Sang Yoon Kim, Ick Chan Kwon, Kwang Meyung Kim, Cheol Hee Ahn

Research output: Contribution to journalArticle

116 Citations (Scopus)

Abstract

"Chemical Equation Presented" Gold nanoprobe: Heparin-DOPAcoated gold nanoparticles (HEPAAuNPs) showed low toxicity, prolonged stability, and an enhanced Xray absorption coefficient in vitro. In vivo microCT images showed that HEPA-AuNPs produced enhanced liver-specific CT images compared with iodine-based contrast agents, thus highlighting its potential as a novel, liver-specific CT imaging agent (see figure).

Original languageEnglish
JournalChemistry - A European Journal
Volume15
Issue number48
DOIs
Publication statusPublished - 2009 Dec 14
Externally publishedYes

Fingerprint

Gold
Liver
Heparin
Nanoprobes
Imaging techniques
X-Ray Microtomography
Iodine
Nanoparticles
Contrast Media
Toxicity
X-Rays
In Vitro Techniques

Keywords

  • Computed tomography
  • Gold
  • Heparin
  • Imaging agents
  • Nanoparticles

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Sun, I. C., Eun, D. K., Na, J. H., Lee, S., Kim, I. I. J., Youn, I. C., ... Ahn, C. H. (2009). Heparin-Coated gold nanopartieles for liver-Specific CT imaging. Chemistry - A European Journal, 15(48). https://doi.org/10.1002/chem.200902344

Heparin-Coated gold nanopartieles for liver-Specific CT imaging. / Sun, In Cheol; Eun, Dae Kyung; Na, Jin Hee; Lee, Seulki; Kim, I. I Jin; Youn, In Chan; Ko, Chang Yong; Kim, Han Sung; Lim, Dohyung; Choi, Kuiwon; Messersmith, Phillip B.; Park, Tae Gwan; Kim, Sang Yoon; Kwon, Ick Chan; Kim, Kwang Meyung; Ahn, Cheol Hee.

In: Chemistry - A European Journal, Vol. 15, No. 48, 14.12.2009.

Research output: Contribution to journalArticle

Sun, IC, Eun, DK, Na, JH, Lee, S, Kim, IIJ, Youn, IC, Ko, CY, Kim, HS, Lim, D, Choi, K, Messersmith, PB, Park, TG, Kim, SY, Kwon, IC, Kim, KM & Ahn, CH 2009, 'Heparin-Coated gold nanopartieles for liver-Specific CT imaging', Chemistry - A European Journal, vol. 15, no. 48. https://doi.org/10.1002/chem.200902344
Sun, In Cheol ; Eun, Dae Kyung ; Na, Jin Hee ; Lee, Seulki ; Kim, I. I Jin ; Youn, In Chan ; Ko, Chang Yong ; Kim, Han Sung ; Lim, Dohyung ; Choi, Kuiwon ; Messersmith, Phillip B. ; Park, Tae Gwan ; Kim, Sang Yoon ; Kwon, Ick Chan ; Kim, Kwang Meyung ; Ahn, Cheol Hee. / Heparin-Coated gold nanopartieles for liver-Specific CT imaging. In: Chemistry - A European Journal. 2009 ; Vol. 15, No. 48.
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