Heparin-Coated gold nanopartieles for liver-Specific CT imaging

In Cheol Sun; Dae Kyung Eun; Jin Hee Na; Seulki Lee; I. I.Jin Kim; In Chan Youn; Chang Yong Ko; Han Sung Kim; Dohyung Lim; Kuiwon Choi; Phillip B. Messersmith; Tae Gwan Park; Sang Yoon Kim; Ick Chan Kwon; Kwangmeyung Kim; Cheol Hee Ahn

doi:10.1002/chem.200902344

Heparin-Coated gold nanopartieles for liver-Specific CT imaging

In Cheol Sun, Dae Kyung Eun, Jin Hee Na, Seulki Lee, I. I.Jin Kim, In Chan Youn, Chang Yong Ko, Han Sung Kim, Dohyung Lim, Kuiwon Choi, Phillip B. Messersmith, Tae Gwan Park, Sang Yoon Kim, Ick Chan Kwon, Kwangmeyung Kim, Cheol Hee Ahn

KU-KIST Graduate School of Converging Science and Technology

Research output: Contribution to journal › Article › peer-review

125 Citations (Scopus)

Abstract

"Chemical Equation Presented" Gold nanoprobe: Heparin-DOPAcoated gold nanoparticles (HEPAAuNPs) showed low toxicity, prolonged stability, and an enhanced Xray absorption coefficient in vitro. In vivo microCT images showed that HEPA-AuNPs produced enhanced liver-specific CT images compared with iodine-based contrast agents, thus highlighting its potential as a novel, liver-specific CT imaging agent (see figure).

Original language	English
Pages (from-to)	13341-13347+13276
Journal	Chemistry - A European Journal
Volume	15
Issue number	48
DOIs	https://doi.org/10.1002/chem.200902344
Publication status	Published - 2009 Dec 14

Keywords

Computed tomography
Gold
Heparin
Imaging agents
Nanoparticles

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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Heparin-Coated gold nanopartieles for liver-Specific CT imaging. / Sun, In Cheol; Eun, Dae Kyung; Na, Jin Hee; Lee, Seulki; Kim, I. I.Jin; Youn, In Chan; Ko, Chang Yong; Kim, Han Sung; Lim, Dohyung; Choi, Kuiwon; Messersmith, Phillip B.; Park, Tae Gwan; Kim, Sang Yoon; Kwon, Ick Chan; Kim, Kwangmeyung; Ahn, Cheol Hee.

In: Chemistry - A European Journal, Vol. 15, No. 48, 14.12.2009, p. 13341-13347+13276.

Research output: Contribution to journal › Article › peer-review

Sun, In Cheol ; Eun, Dae Kyung ; Na, Jin Hee ; Lee, Seulki ; Kim, I. I.Jin ; Youn, In Chan ; Ko, Chang Yong ; Kim, Han Sung ; Lim, Dohyung ; Choi, Kuiwon ; Messersmith, Phillip B. ; Park, Tae Gwan ; Kim, Sang Yoon ; Kwon, Ick Chan ; Kim, Kwangmeyung ; Ahn, Cheol Hee. / Heparin-Coated gold nanopartieles for liver-Specific CT imaging. In: Chemistry - A European Journal. 2009 ; Vol. 15, No. 48. pp. 13341-13347+13276.

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