Heparinized small intestinal submucosa (SIS) for cardiovascular applications

K. S. Jee, H. D. Park, J. S. Shin, K. D. Park

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The development of heparinized small intestinal submucosa (SIS) for cardiovascular bioprothesis was discussed. The heparinized SIS was investigated in vitro and in vivo to improve the blood compatibility, cell attachment and calcification resistibility. The in vitro evaluation involves the activated-partial thromboplastin time (APTT), resistance to enzyme digestion and cell attachment. The cell attachment results show that the heparinized SIS attached had higher fibroblast than fresh SIS.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)


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