Hepatic and pulmonary nodular lesions in pediatric urinary tract infections

Hyung-Eun Yim, Byung Min Choi, Young-Jun Rhie, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee

Research output: Contribution to journalArticle

Abstract

One of the major goals in investigating children with urinary tract infection (UTI) is to recognize patients at risk of further UTI-related problems. This study reports the clinical features of 19 pediatric patients with UTIs in whom associated hepatic and/or pulmonary nodules were incidentally diagnosed by the imaging tests performed for the UTI. Hepatic nodules in five patients were detected on ultrasound scans, and pulmonary nodules and both hepatic and pulmonary nodules were detected in 12 and two children by dimercaptosuccinic acid scintigraphy. The mean age of the patients was 24.5 months. Vesicoureteral reflux (VUR) was detected in nine of 17 patients (52.9%), acute pyelonephritis was identified in nine of 18 patients, and renal scarring was found in 57.1% patients with pyelonephritis. On follow-up, the hepatic and/or pulmonary nodules regressed in all patients. About 85.7% of patients experienced a recurrence of UTI within 1 year. In comparison with age- and sex-matched controls with UTIs without pulmonary or hepatic nodules, the presence of VUR and the recurrence of UTI within 1 year were higher in patients with UTIs and nodules (P∈<∈0.05). The hepatic and/or pulmonary nodules identified on the ultrasound scan and by dimercaptosuccinic acid scintigraphy may provide a valuable diagnostic marker for the proper management of patients with an UTI.

Original languageEnglish
Pages (from-to)425-431
Number of pages7
JournalPediatric Nephrology
Volume26
Issue number3
DOIs
Publication statusPublished - 2011 Mar 1

Fingerprint

Urinary Tract Infections
Pediatrics
Lung
Liver
Succimer
Vesico-Ureteral Reflux
Pyelonephritis
Radionuclide Imaging
Recurrence
Cicatrix
Kidney

Keywords

  • Child
  • Risk assessment
  • Technetium Tc 99 m dimercaptosuccinic acid
  • Ultrasonography
  • Urinary tract infection

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Hepatic and pulmonary nodular lesions in pediatric urinary tract infections. / Yim, Hyung-Eun; Choi, Byung Min; Rhie, Young-Jun; Yoo, Kee Hwan; Hong, Young Sook; Lee, Joo Won.

In: Pediatric Nephrology, Vol. 26, No. 3, 01.03.2011, p. 425-431.

Research output: Contribution to journalArticle

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