Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-Activated Receptor Alpha Network

Agriculture & Biology

• peroxisome proliferator-activated receptor alpha 77%
• histones 51%
• lysine 44%
• fatty liver 44%
• liver 31%
• lipids 28%
• hepatocytes 23%
• apolipoprotein E2 17%
• transcriptomics 15%
• histone demethylases 14%
• liver diseases 11%
• disease prevention 10%
• metabolic diseases 10%
• mice 10%
• gene regulatory networks 9%
• DNA microarrays 9%
• high fat diet 9%
• etiology 9%
• epigenetics 8%
• methylation 8%
• pathogenesis 8%
• chromatin 7%
• transcriptome 7%
• genes 6%
• genomics 5%
• gene expression 5%
• metabolism 5%

Medicine & Life Sciences

• PPAR alpha 68%
• histone H3 trimethyl Lys4 55%
• Lysine 52%
• Histones 50%
• Lipids 35%
• Liver 27%
• Non-alcoholic Fatty Liver Disease 24%
• Chromatin Immunoprecipitation Sequencing 19%
• Hepatocytes 19%
• Gene Expression Profiling 15%
• Jumonji Domain-Containing Histone Demethylases 14%
• Apolipoprotein E2 11%
• Chromatin Assembly and Disassembly 8%
• Gene Regulatory Networks 8%
• Metabolic Diseases 8%
• Oligonucleotide Array Sequence Analysis 7%
• High Fat Diet 7%
• Transcriptome 7%
• Methylation 6%
• Epigenomics 6%
• Liver Diseases 6%
• Genes 6%
• Chronic Disease 5%
• Diet 5%

Chemical Compounds

• H3K4Me3 100%
• Histone 57%
• Lysine 50%
• Lipid 36%
• Apolipoprotein 13%
• Microarrays 11%
• Metabolic 8%