Hepatocellular carcinoma: Power Doppler US with a contrast agent - Preliminary results

Ah Young Kim, Byung Ihn Choi, Tae Kyoung Kim, Joon Koo Han, Eun Joo Yun, Ki Yeol Lee, Man Chung Han

Research output: Contribution to journalArticle

132 Citations (Scopus)

Abstract

PURPOSE: To investigate the value of contrast material-enhanced power Doppler ultrasonography (US) in the demonstration and characterization of tumor vascularity in hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Twenty patients with HCC were prospectively evaluated with power Doppler US before and after injection of the contrast agent SH U 508 A. The grade and pattern of tumor vascularity at power Doppler US were analyzed, along with the degree of tumor staining at angiography. RESULTS: Intra- and peritumoral flow signals were detected in 19 HCCs (95%) at unenhanced power Doppler US. After injection of contrast agent, flow signals increased in 19 lesions (95%). At contrast-enhanced power Doppler US, two tumors demonstrated grade 1 vascularity; four grade 2; three, grade 3; and 11, grade 4. At angiography, two tumors demonstrated grade 1 staining; four grade 2; eight, grade 3; six, grade 4. The correlation between vascularity grades at contrast-enhanced power Doppler US and at angiography was statistically significant (P < .0001). Seventeen HCCs (85%) showed the intratumoral or basket pattern of vascularity at unenhanced power Doppler US; after injection of contrast material, 15 HCCs (75%) showed the mixed pattern. CONCLUSION: Contrast- enhanced power Doppler US is superior to unenhanced power Doppler US in the demonstration and characterization of tumor vascularity in HCC.

Original languageEnglish
Pages (from-to)135-140
Number of pages6
JournalRadiology
Volume209
Issue number1
DOIs
Publication statusPublished - 1998 Jan 1
Externally publishedYes

Fingerprint

Doppler Ultrasonography
Contrast Media
Hepatocellular Carcinoma
Neoplasms
Angiography
Injections
Staining and Labeling

Keywords

  • Contrast media
  • Galactose
  • Liver neoplasms, blood supply
  • Ultrasound (US), contrast media
  • Ultrasound (US), power Doppler studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Kim, A. Y., Choi, B. I., Kim, T. K., Han, J. K., Yun, E. J., Lee, K. Y., & Han, M. C. (1998). Hepatocellular carcinoma: Power Doppler US with a contrast agent - Preliminary results. Radiology, 209(1), 135-140. https://doi.org/10.1148/radiology.209.1.9769824

Hepatocellular carcinoma : Power Doppler US with a contrast agent - Preliminary results. / Kim, Ah Young; Choi, Byung Ihn; Kim, Tae Kyoung; Han, Joon Koo; Yun, Eun Joo; Lee, Ki Yeol; Han, Man Chung.

In: Radiology, Vol. 209, No. 1, 01.01.1998, p. 135-140.

Research output: Contribution to journalArticle

Kim, Ah Young ; Choi, Byung Ihn ; Kim, Tae Kyoung ; Han, Joon Koo ; Yun, Eun Joo ; Lee, Ki Yeol ; Han, Man Chung. / Hepatocellular carcinoma : Power Doppler US with a contrast agent - Preliminary results. In: Radiology. 1998 ; Vol. 209, No. 1. pp. 135-140.
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