Hepatoid thymic carcinoma: A case report

Jeong Hyeon Lee, Hyunchul Kim, Yang Seok Chae, Nam Hee Won, Jong Sang Choi, Chul Hwan Kim

Research output: Contribution to journalArticle

Abstract

We report here on a rare case of hepatoid thymic carcinoma in a 34-year-old man. The patient complained of a high fever and headache, and a 6.6cm-sized anterior mediastinal mass was found on chest computed tomography (CT). There was no hepatic mass seen on abdominal CT. The resected mass consisted of epithelioid cells with abundant eosinophilic cytoplasm, pleomorphic vesicular nuclei and prominent nucleoli, and the mass was surrounded by thymic tissue. The tumor cells were immunopositive for cytokeratin 7, α-1-antitrypsin, hepatocyte staining, and epithelial membrane antigen, but they were negative for CD5, α-fetoprotein (AFP) and placental alkaline phosphatase, and this all led to a diagnosis of hepatoid thymic carcinoma rather than hepatoid yolk sac tumor. This entity should be included in the differential diagnosis of epithelioid thymic tumors.

Original languageEnglish
Pages (from-to)562-565
Number of pages4
JournalKorean Journal of Pathology
Volume43
Issue number6
DOIs
Publication statusPublished - 2009 Dec 1

Fingerprint

Thymoma
Tomography
Fetal Proteins
Thymus Neoplasms
Keratin-7
Endodermal Sinus Tumor
Epithelioid Cells
Mucin-1
Headache
Hepatocytes
Cytoplasm
Differential Diagnosis
Fever
Thorax
Staining and Labeling
Liver
Neoplasms
placental alkaline phosphatase

Keywords

  • Carcinoma
  • Hepatocellular
  • Thymus
  • Thymus neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Hepatoid thymic carcinoma : A case report. / Lee, Jeong Hyeon; Kim, Hyunchul; Chae, Yang Seok; Won, Nam Hee; Choi, Jong Sang; Kim, Chul Hwan.

In: Korean Journal of Pathology, Vol. 43, No. 6, 01.12.2009, p. 562-565.

Research output: Contribution to journalArticle

Lee, Jeong Hyeon ; Kim, Hyunchul ; Chae, Yang Seok ; Won, Nam Hee ; Choi, Jong Sang ; Kim, Chul Hwan. / Hepatoid thymic carcinoma : A case report. In: Korean Journal of Pathology. 2009 ; Vol. 43, No. 6. pp. 562-565.
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