High molecular weight poly(l-lactide) and its microsphere synthesized in the supercritical dimethyl ether

Cheol Soo Yoon, Hyun Deok Park, Se Yoon Kim, Soo Hyun Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The ring-opening polymerization of L-lactide initiated by stannous octoate was carried out in supercritical dimethylether(scDME) at various reaction conditions (time and temperature). The monomer conversion increased to ca. 90% on increasing the reaction time to ihr. The molecular weight of the poly(L-lactide)(PLLA) also increased to ca. 160,000 g · mol-1 over the same period. Increasing reaction temperature from 118 to 135°C or reaction pressure from 280 to 520 bar resulted in increased monomer conversion and molecular weight. After the polymerization, PLLA microspheres were prepared in situ by using a continuous supercritical anti-solvent process without residual organic solvent.

Original languageEnglish
Pages (from-to)515-520
Number of pages6
JournalMacromolecular Symposia
Volume249-250
DOIs
Publication statusPublished - 2007 Aug 1
Externally publishedYes

Fingerprint

Microspheres
Ethers
molecular weight
ethers
Monomers
Molecular weight
Ring opening polymerization
polymerization
monomers
Organic solvents
Polymerization
reaction time
Temperature
temperature
rings
dilactide
poly(lactide)
dimethyl ether
2-ethylhexanoic acid tin(II) salt

Keywords

  • DME
  • Microsphere
  • PLLA
  • Polymerization
  • Supercritical fluid

ASJC Scopus subject areas

  • Polymers and Plastics
  • Materials Chemistry

Cite this

High molecular weight poly(l-lactide) and its microsphere synthesized in the supercritical dimethyl ether. / Yoon, Cheol Soo; Park, Hyun Deok; Kim, Se Yoon; Kim, Soo Hyun.

In: Macromolecular Symposia, Vol. 249-250, 01.08.2007, p. 515-520.

Research output: Contribution to journalArticle

Yoon, Cheol Soo ; Park, Hyun Deok ; Kim, Se Yoon ; Kim, Soo Hyun. / High molecular weight poly(l-lactide) and its microsphere synthesized in the supercritical dimethyl ether. In: Macromolecular Symposia. 2007 ; Vol. 249-250. pp. 515-520.
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