High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography

Jae Ho Han, Xuan Liu, Jin U. Kang, Chul Gyu Song

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We demonstrate the subsurface imaging of an articular cartilage using Fourier-domain common-path optical coherence tomography. The bare fiber probe integrated with a hypodermic needle provides the rigidness required to perform lateral scanning with less microscale bending. By submerging both the probe and the specimen into saline solution, we not only reduce the beam divergence, but also increase the signal-to-noise ratio compared with the measurement in free space. Our system can differentiate the characteristic cartilage zones and identity various micro-structured defects in an ex vivo chicken knee cartilage, thus demonstrating that it could be used to conduct early arthritis diagnosis and intraoperative endo-microscopy.

Original languageEnglish
Pages (from-to)167-169
Number of pages3
JournalChinese Optics Letters
Volume8
Issue number2
DOIs
Publication statusPublished - 2010 Feb 1
Externally publishedYes

Fingerprint

cartilage
Optical tomography
Cartilage
optical paths
tomography
Imaging techniques
high resolution
arthritis
chickens
probes
Sodium Chloride
needles
microbalances
Needles
submerging
Signal to noise ratio
divergence
Microscopic examination
signal to noise ratios
microscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography. / Han, Jae Ho; Liu, Xuan; Kang, Jin U.; Song, Chul Gyu.

In: Chinese Optics Letters, Vol. 8, No. 2, 01.02.2010, p. 167-169.

Research output: Contribution to journalArticle

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