High-sensitive, direct and label-free detection technique of nanotoxic material using QCM

Chanho Park, Kuewhan Jang, Sangmyung Lee, Juneseok You, Jinsung Park, Sung Soo Na

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial in real life. However, high toxicity of those materials has been reported and the detection method is required for human health and environment. In present study, high-sensitive, label-free detection methods of nanotoxic materials are described. We have developed a sensitive and selective quart crystal microbalance (QCM) based sensor for detection of nanotoxic materials by using frequency shift. In this study, we propose the sensitive in situ detection of nanotoxic materials by using QCM functionalized with a specific DNA for a target material. It also allows the detection of target material rapidly in real time. In contrast to the conventional methods, this method is label-free and sensitive, capable of direct rapid detection and real-time monitoring. The results suggest that QCM-based detection opens a new avenue for the development of a practical water-testing sensor.

Original languageEnglish
Title of host publicationNSTI: Biotech, Biomaterials and Biomedical - TechConnect Briefs 2015
PublisherTaylor and Francis Inc.
Pages180-182
Number of pages3
Volume3
ISBN (Electronic)9781498747295
Publication statusPublished - 2015
Event10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference - Washington, United States
Duration: 2015 Jun 142015 Jun 17

Other

Other10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference
CountryUnited States
CityWashington
Period15/6/1415/6/17

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Keywords

  • Label-free detection
  • Nanomaterial
  • Quart crystal microbalance
  • Resonance frequency
  • Toxicity

ASJC Scopus subject areas

  • Surfaces, Coatings and Films
  • Fluid Flow and Transfer Processes
  • Biotechnology
  • Fuel Technology

Cite this

Park, C., Jang, K., Lee, S., You, J., Park, J., & Na, S. S. (2015). High-sensitive, direct and label-free detection technique of nanotoxic material using QCM. In NSTI: Biotech, Biomaterials and Biomedical - TechConnect Briefs 2015 (Vol. 3, pp. 180-182). Taylor and Francis Inc..