High Stability of a Donor-Acceptor Type Oxazepine-Containing Fluorophore and Its Applications in Cellular Imaging and Two-Photon Deep Tissue Imaging

Heejo Moon, Yuna Jung, Youngseo Kim, Byeong Wook Kim, Jin Gyu Choi, Na Hee Kim, Myung Sook Oh, Sungnam Park, B. Moon Kim, Dokyoung Kim

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

A new donor (D)-acceptor (A) type naphthalene-based oxazepine-containing fluorophore, OXN-1, is reported, which shows unusually high stability in various environments. Its photophysical properties and structural stabilities under harsh conditions are thoroughly examined. The high stability of OXN-1 is explained by quantum chemical calculations. Its exceptional bioimaging capabilities for cells with low cytotoxicity are verified. In addition, its deep tissue imaging ability with two-photon microscopy (TPM) is evaluated.

Original languageEnglish
Pages (from-to)3891-3894
Number of pages4
JournalOrganic Letters
Volume21
Issue number11
DOIs
Publication statusPublished - 2019 Jun 7

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'High Stability of a Donor-Acceptor Type Oxazepine-Containing Fluorophore and Its Applications in Cellular Imaging and Two-Photon Deep Tissue Imaging'. Together they form a unique fingerprint.

Cite this