Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2′-hydroxy-1 ,1′-binaphthyl

Seung Wan Kang, Dong Hyun Ko, Kyoung Hoon Kim, Deok-Chan Ha

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

(Equation presented) A new N-triflated amino alcohol-titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.

Original languageEnglish
Pages (from-to)4517-4519
Number of pages3
JournalOrganic Letters
Volume5
Issue number23
DOIs
Publication statusPublished - 2003 Nov 13

Fingerprint

aldehydes
Aldehydes
alcohols
Amino Alcohols
Enantioselectivity
Titanium
titanium
Alcohols
Ligands
catalysts
ligands
Catalysts
diethylzinc

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2′-hydroxy-1 ,1′-binaphthyl. / Kang, Seung Wan; Ko, Dong Hyun; Kim, Kyoung Hoon; Ha, Deok-Chan.

In: Organic Letters, Vol. 5, No. 23, 13.11.2003, p. 4517-4519.

Research output: Contribution to journalArticle

@article{e6891e743d344626ad99900d23cbd2f5,
title = "Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2′-hydroxy-1 ,1′-binaphthyl",
abstract = "(Equation presented) A new N-triflated amino alcohol-titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.",
author = "Kang, {Seung Wan} and Ko, {Dong Hyun} and Kim, {Kyoung Hoon} and Deok-Chan Ha",
year = "2003",
month = "11",
day = "13",
doi = "10.1021/ol0358511",
language = "English",
volume = "5",
pages = "4517--4519",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "23",

}

TY - JOUR

T1 - Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2′-hydroxy-1 ,1′-binaphthyl

AU - Kang, Seung Wan

AU - Ko, Dong Hyun

AU - Kim, Kyoung Hoon

AU - Ha, Deok-Chan

PY - 2003/11/13

Y1 - 2003/11/13

N2 - (Equation presented) A new N-triflated amino alcohol-titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.

AB - (Equation presented) A new N-triflated amino alcohol-titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.

UR - http://www.scopus.com/inward/record.url?scp=0344496713&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0344496713&partnerID=8YFLogxK

U2 - 10.1021/ol0358511

DO - 10.1021/ol0358511

M3 - Article

VL - 5

SP - 4517

EP - 4519

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 23

ER -