Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2′-hydroxy-1 ,1′-binaphthyl

Seung Wan Kang, Dong Hyun Ko, Kyoung Hoon Kim, Deok-Chan Ha

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

(Equation presented) A new N-triflated amino alcohol-titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.

Original languageEnglish
Pages (from-to)4517-4519
Number of pages3
JournalOrganic Letters
Volume5
Issue number23
DOIs
Publication statusPublished - 2003 Nov 13

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ASJC Scopus subject areas

  • Molecular Medicine

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