Highly Selective and Sensitive Detection of Breath Isoprene by Tailored Gas Reforming: A Synergistic Combination of Macroporous WO3 Spheres and Au Catalysts

Sei Woong Park, Seong Yong Jeong, Young Kook Moon, Ki Beom Kim, Ji Wook Yoon, Jong Heun Lee

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Precise detection of breath isoprene can provide valuable information for monitoring the physical and physiological status of human beings or for the early diagnosis of cardiovascular diseases. However, the extremely low concentration and low chemical reactivity of breath isoprene hamper the selective and sensitive detection of isoprene using oxide semiconductor chemiresistors. Herein, we report that macroporous WO3 microspheres whose inner macropores are surrounded by Au nanoparticles exhibit a high response (resistance ratio = 11.3) to 0.1 ppm isoprene under highly humid conditions at 275 °C and an extremely low detection limit (0.2 ppb). Furthermore, the sensor showed excellent selectivity to isoprene over five interferants that could be exhaled by humans. Notably, the selectivity to isoprene is critically dependent on the location of Au nanocatalysts and macroporosity. The mechanism underlying the selective isoprene detection is investigated in relation to the reforming of less reactive isoprene into more reactive intermediate species promoted by macroporous catalytic reactors, which is confirmed by the analysis using a proton transfer reaction quadrupole mass spectrometer. The sensor for breath analysis has high potential for simple physical and physiological monitoring as well as disease diagnosis.

Original languageEnglish
Pages (from-to)11587-11596
Number of pages10
JournalACS Applied Materials and Interfaces
Volume14
Issue number9
DOIs
Publication statusPublished - 2022 Mar 9

Keywords

  • breath analysis
  • gas reforming
  • gas sensors
  • isoprene
  • microreactor

ASJC Scopus subject areas

  • Materials Science(all)

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