Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi

Jun Feng Zhang, Lin E. Guo, Tie Nan Zang, Yu Lian Duan, Xin Yi Liu, Zhigang Yang, Peter Verwilst, Kaijun Luo, Guang Ke Wang, Jun Feng Kou, Ying Zhou, Jong Seung Kim

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A chemodosimeter was designed to function as a highly selective phosphate ion (Pi) sensor, showing a 91-fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase-catalyzed Pi generation and was the first probe able to trace the generation and enrichment of Pi through hemichannel closure in Sf9 cells.

Original languageEnglish
Pages (from-to)1165-1169
Number of pages5
JournalChemistry - An Asian Journal
Volume10
Issue number5
DOIs
Publication statusPublished - 2015 May 1

Keywords

  • 1 8-naphthalene imide
  • fluorescent probes
  • in vivo imaging
  • inorganic phosphate
  • sensors

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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  • Cite this

    Zhang, J. F., Guo, L. E., Zang, T. N., Duan, Y. L., Liu, X. Y., Yang, Z., Verwilst, P., Luo, K., Wang, G. K., Kou, J. F., Zhou, Y., & Kim, J. S. (2015). Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi. Chemistry - An Asian Journal, 10(5), 1165-1169. https://doi.org/10.1002/asia.201500091