Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Yun Hak Lee, Wen Xiu Ren, Jiyou Han, Kyoung Sunwoo, Ja Yun Lim, Jong-Hoon Kim, Jong Seung Kim

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

Original languageEnglish
Pages (from-to)14401-14404
Number of pages4
JournalChemical Communications
Volume51
Issue number76
DOIs
Publication statusPublished - 2015 Jul 31

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Homocysteine
Medical problems
Cardiomyopathies
Fluorescent Dyes
Photons
Glutathione
Cysteine
Tissue
Imaging techniques
Health
Neoplasms

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

Highly selective two-photon imaging of cysteine in cancerous cells and tissues. / Lee, Yun Hak; Ren, Wen Xiu; Han, Jiyou; Sunwoo, Kyoung; Lim, Ja Yun; Kim, Jong-Hoon; Kim, Jong Seung.

In: Chemical Communications, Vol. 51, No. 76, 31.07.2015, p. 14401-14404.

Research output: Contribution to journalArticle

Lee, Yun Hak ; Ren, Wen Xiu ; Han, Jiyou ; Sunwoo, Kyoung ; Lim, Ja Yun ; Kim, Jong-Hoon ; Kim, Jong Seung. / Highly selective two-photon imaging of cysteine in cancerous cells and tissues. In: Chemical Communications. 2015 ; Vol. 51, No. 76. pp. 14401-14404.
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