Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Yun Hak Lee; Wen Xiu Ren; Jiyou Han; Kyoung Sunwoo; Ja Yun Lim; Jong-Hoon Kim; Jong Seung Kim

doi:10.1039/c5cc06038a

Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Yun Hak Lee, Wen Xiu Ren, Jiyou Han, Kyoung Sunwoo, Ja Yun Lim, Jong-Hoon Kim, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

Original language	English
Pages (from-to)	14401-14404
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	76
DOIs	https://doi.org/10.1039/c5cc06038a
Publication status	Published - 2015 Jul 31

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c5cc06038a

Cite this

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title = "Highly selective two-photon imaging of cysteine in cancerous cells and tissues",

abstract = "Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.",

author = "Lee, {Yun Hak} and Ren, {Wen Xiu} and Jiyou Han and Kyoung Sunwoo and Lim, {Ja Yun} and Jong-Hoon Kim and Kim, {Jong Seung}",

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AU - Lee, Yun Hak

AU - Ren, Wen Xiu

AU - Han, Jiyou

AU - Sunwoo, Kyoung

AU - Lim, Ja Yun

AU - Kim, Jong-Hoon

AU - Kim, Jong Seung

PY - 2015/7/31

Y1 - 2015/7/31

N2 - Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

AB - Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

UR - http://www.scopus.com/inward/record.url?scp=84941202286&partnerID=8YFLogxK

U2 - 10.1039/c5cc06038a

DO - 10.1039/c5cc06038a

M3 - Article

C2 - 26271369

AN - SCOPUS:84941202286

SN - 1359-7345

VL - 51

SP - 14401

EP - 14404

JO - Chemical Communications

JF - Chemical Communications

IS - 76

ER -

Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Abstract

ASJC Scopus subject areas

UN SDGs

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